GOLM2 - golgi membrane protein 2 Gene

Homo sapiens

Also known as H63; CASC4

Gene ID: 113201 | Gene type: protein coding

About GOLM2

This gene has 12 transcripts (splice variants), 205 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 38.2), adrenal (RPKM 35.0) and 25 other tissues.

Summary

The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Dec 2010]

GOLM2 Products(2)

mRNA	Protein	Name
NM_138423.4	NP_612432.2	protein GOLM2 isoform a
NM_177974.3	NP_816929.1	protein GOLM2 isoform b

Protein Preferred Names

Protein Names

protein GOLM2

cancer susceptibility 4

Related Diseases

Diseases

Alias

Schizophrenia 5

SCZD5	Schizophrenia Susceptibility Locus, Chromosome 6q-Related
Schizophrenia 5 With Or Without An Affective Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05593	GOLM2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	GOLM2	VGNC	VGNC:99200
Mus musculus	GOLM2	MGD	MGI:2443129
Bos taurus	GOLM2	VGNC	VGNC:84818
Rattus norvegicus	GOLM2	RGD	RGD:1305985
Felis catus	GOLM2	VGNC	VGNC:84871
Canis familiaris	GOLM2	VGNC	VGNC:84817

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