SCRG1 - stimulator of chondrogenesis 1 Gene

Homo sapiens

Also known as SCRG-1

Gene ID: 11341 | Gene type: protein coding

About SCRG1

Cytogenetic location: 4q34.1 Genomic coordinates (GRCh38): 4:173,384,701-173,519,144 (from NCBI)

This gene has 2 transcripts (splice variants) and 142 orthologues. Biased expression in brain (RPKM 46.0), testis (RPKM 30.3) and 3 other tissues.

Summary

Scrapie-responsive gene 1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The scrapie responsive protein 1 may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus. In addition, the encoded protein can interact with bone marrow stromal cell antigen 1 (BST1) to enhance the differentiation potentials of human mesenchymal stem cells during tissue and bone regeneration. [provided by RefSeq, Jul 2016]

SCRG1 Products(2)

mRNA	Protein	Name
NM_001329597.2	NP_001316526.1	scrapie-responsive protein 1 precursor
NM_007281.4	NP_009212.1	scrapie-responsive protein 1 precursor

SCRG1 Protein Structure

SCRG1

0
98 a.a.

Protein Preferred Names

Protein Names

scrapie-responsive protein 1

scrapie responsive gene 1

Related Diseases

Diseases

Alias

Scrapie

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12561	SCRG1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SCRG1	VGNC	VGNC:50423
Mus musculus	SCRG1	MGD	MGI:1328308
Felis catus	SCRG1	VGNC	VGNC:64934
Bos taurus	SCRG1	VGNC	VGNC:34364
Rattus norvegicus	SCRG1	RGD	RGD:68377

Name
Email *

	Sorry, but the email address you supplied was invalid.