2. Gene
  3. PGLYRP2 - peptidoglycan recognition protein 2 Gene

PGLYRP2 - peptidoglycan recognition protein 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as tagL; PGRPL; PGRP-L; PGLYRPL; HMFT0141; TAGL-like; tagl-beta; tagL-alpha

Gene ID: 114770 | Gene type: protein coding

About PGLYRP2

Cytogenetic location: 19p13.12 Genomic coordinates (GRCh38): 19:15,468,645-15,479,501 (from NCBI)

This gene has 4 transcripts (splice variants), 274 orthologues and 3 paralogues. Restricted expression toward liver (RPKM 52.9).

Summary

This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. This protein hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in Bacterial cell wall glycopeptides, and thus may play a scavenger role by digesting biologically active peptidoglycan into biologically inactive fragments. [provided by RefSeq, Sep 2011]

PGLYRP2 Products(2)

mRNA Protein Name
NM_001363546.1 NP_001350475.1 N-acetylmuramoyl-L-alanine amidase isoform 2 precursor
NM_052890.4 NP_443122.3 N-acetylmuramoyl-L-alanine amidase isoform 1 precursor

PGLYRP2 Protein Structure

Amidase_2

Amidase_2: N-acetylmuramoyl-L-alanine amidase (404 - 533)

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  • 576 a.a.
Protein Preferred Names Protein Names

N-acetylmuramoyl-L-alanine amidase

peptidoglycan recognition protein L

Recombinant PGLYRP2 Proteins

Cat. No. Product Name Accession Purity
HY-P71844 PGLYRP2/PGRP-L Protein, Human (P.pastoris, His) Q96PD5 (22S-576Q) ≥95%

Related Diseases

Diseases Alias
Cicatricial Entropion
Febrile Seizures, Familial, 4

FEB4

Convulsions, Familial Febrile, 4

Familial Febrile Seizures 4

Familial Febrile Convulsions 4
Meester-Loeys Syndrome

MRLS
Familial Febrile Seizures

Familial Febrile Convulsions

Feb

Febrile Seizures, Familial
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10388 PGLYRP2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta PGLYRP2 VGNC VGNC:75887
Canis familiaris PGLYRP2 VGNC VGNC:44462
Mus musculus PGLYRP2 MGD MGI:1928099
Bos taurus PGLYRP2 VGNC VGNC:32792
Rattus norvegicus PGLYRP2 RGD RGD:1359183
Felis catus PGLYRP2 VGNC VGNC:64123
Others PGLYRP2 NCBI