2. Gene
  3. CSMD2 - CUB and Sushi multiple domains 2 Gene

CSMD2 - CUB and Sushi multiple domains 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as dJ947L8.1; dJ1007G16.1; dJ1007G16.2

Gene ID: 114784 | Gene type: protein coding

About CSMD2

Cytogenetic location: 1p35.1 Genomic coordinates (GRCh38): 1:33,513,998-34,165,842 (from NCBI)

This gene has 9 transcripts (splice variants), 138 orthologues and 39 paralogues. Low expression observed in reference dataset.

Summary

The protein encoded by this gene is thought to be involved in the control of complement cascade of the immune system. Defects in this gene have been associated with schizophrenia. This gene may act as a tumor suppressor for colorectal Cancer. [provided by RefSeq, Jan 2020]

CSMD2 Products(2)

mRNA Protein Name
NM_001281956.2 NP_001268885.1 CUB and sushi domain-containing protein 2 isoform 1
NM_052896.5 NP_443128.2 CUB and sushi domain-containing protein 2 isoform 2

CSMD2 Protein Structure

CUB

CUB: CUB domain (26 - 131)

Sushi

Sushi: Sushi repeat (SCR repeat) (139 - 196)

CUB

CUB: CUB domain (202 - 303)

Sushi

Sushi: Sushi repeat (SCR repeat) (343 - 400)

CUB

CUB: CUB domain (405 - 513)

Sushi

Sushi: Sushi repeat (SCR repeat) (521 - 574)

CUB

CUB: CUB domain (578 - 683)

Sushi

Sushi: Sushi repeat (SCR repeat) (691 - 748)

CUB

CUB: CUB domain (752 - 857)

Sushi

Sushi: Sushi repeat (SCR repeat) (867 - 920)

CUB

CUB: CUB domain (924 - 1031)

Sushi

Sushi: Sushi repeat (SCR repeat) (1039 - 1094)

CUB

CUB: CUB domain (1098 - 1203)

Sushi

Sushi: Sushi repeat (SCR repeat) (1211 - 1267)

CUB

CUB: CUB domain (1271 - 1377)

Sushi

Sushi: Sushi repeat (SCR repeat) (1385 - 1441)

CUB

CUB: CUB domain (1445 - 1550)

Sushi

Sushi: Sushi repeat (SCR repeat) (1558 - 1615)

CUB

CUB: CUB domain (1619 - 1724)

Sushi

Sushi: Sushi repeat (SCR repeat) (1742 - 1792)

CUB

CUB: CUB domain (1796 - 1901)

Sushi

Sushi: Sushi repeat (SCR repeat) (1909 - 1964)

CUB

CUB: CUB domain (1968 - 2073)

Sushi

Sushi: Sushi repeat (SCR repeat) (2123 - 2178)

CUB

CUB: CUB domain (2182 - 2277)

Sushi

Sushi: Sushi repeat (SCR repeat) (2294 - 2351)

CUB

CUB: CUB domain (2358 - 2463)

Sushi

Sushi: Sushi repeat (SCR repeat) (2468 - 2526)

Sushi

Sushi: Sushi repeat (SCR repeat) (2531 - 2588)

Sushi

Sushi: Sushi repeat (SCR repeat) (2594 - 2653)

Sushi

Sushi: Sushi repeat (SCR repeat) (2658 - 2711)

Sushi

Sushi: Sushi repeat (SCR repeat) (2716 - 2769)

Sushi

Sushi: Sushi repeat (SCR repeat) (2774 - 2827)

Sushi

Sushi: Sushi repeat (SCR repeat) (2835 - 2888)

Sushi

Sushi: Sushi repeat (SCR repeat) (2893 - 2947)

Sushi

Sushi: Sushi repeat (SCR repeat) (2952 - 3007)

Sushi

Sushi: Sushi repeat (SCR repeat) (3012 - 3065)

Sushi

Sushi: Sushi repeat (SCR repeat) (3070 - 3123)

Sushi

Sushi: Sushi repeat (SCR repeat) (3131 - 3185)

Sushi

Sushi: Sushi repeat (SCR repeat) (3190 - 3245)

  • 0
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  • 1800
  • 2400
  • 3000
  • 3487 a.a.
Protein Preferred Names Protein Names

CUB and sushi domain-containing protein 2

CUB and Sushi (SCR repeat) domain

Related Diseases

Diseases Alias
Neuronitis
Epilepsy, Familial Adult Myoclonic, 1

FAME1

Benign Adult Familial Myoclonic Epilepsy 1

Bafme1

Fcmte1

Cortical Myoclonic Tremor With Epilepsy, Familial, 1

Familial Adult Myoclonic Epilepsy 1

Familial Cortical Myoclonic Tremor And Epilepsy 1

Epilepsy, Myoclonic, Familial Adult, Type 1
Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1
Head And Neck Cancer

Head And Neck Neoplasm

Head And Neck Tumours

Head/Neck Neoplasm

Tumor Of Head And Neck

Head And Neck Neoplasms

Hnc

Cancer, Head/Neck
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03240 CSMD2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CSMD2 RGD RGD:1565728
Mus musculus CSMD2 MGD MGI:2386401
Felis catus CSMD2 VGNC VGNC:61223
Macaca mulatta CSMD2 VGNC VGNC:71441
Bos taurus CSMD2 VGNC VGNC:27762