RNF157 - ring finger protein 157 Gene

Homo sapiens

Gene ID: 114804 | Gene type: protein coding

About RNF157

This gene has 10 transcripts (splice variants), 210 orthologues and 1 paralogue. Biased expression in brain (RPKM 16.0), testis (RPKM 13.4) and 11 other tissues.

Summary

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of signal transduction; positive regulation of dendrite extension; and protein autoubiquitination. Predicted to be located in cell body. Predicted to be active in early endosome; nucleus; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

RNF157 Products(2)

mRNA	Protein	Name
NM_001330501.2	NP_001317430.1	E3 ubiquitin ligase RNF157 isoform 2
NM_052916.3	NP_443148.1	E3 ubiquitin ligase RNF157 isoform 1

RNF157 Protein Structure

zf-C3HC4_3

0
200
400
600
679 a.a.

Protein Preferred Names

Protein Names

E3 ubiquitin ligase RNF157

RING-type E3 ubiquitin transferase RNF157

Related Diseases

Diseases

Alias

Testicular Leydig Cell Tumor

Testicular Leydig Cell Neoplasm	Leydig Cell Tumor Of Testis
Interstitial Cell Neoplasm Of Testis

Testicular Sex Cord-Stromal Neoplasm

Sex Cord-Stromal Tumor Of Testis

Testicular Sex Cord-Stromal Tumor

Carpenter Syndrome 1

Carpenter Syndrome	Acrocephalopolysyndactyly Type Ii
Acps Ii	CRPT1
Acrocephalopolysyndactyly Type 2	Acrocephalosyndactyly, Type Ii
Acrocephalopolysyndactyly 2	Acps2
Acps 2	Type Ii Acrocephalosyndactyly
Carpenter Syndrome, Type 1	Apert-Crouzon Disease

Patent Foramen Ovale

Atrial Septal Defect Within Oval Fossa	Foramen Ovale Patent
Ostium Secundum Atrial Septal Defect	Atrial Septal Defect, Ostium Secundum Type
Foramen Ovale, Patent	Defect, Patent Or Persistent, Ostium Secundum
Ostium Secundum Type Atrial Septal Defect	Persistent Ostium Secundum
Asd Ostium Secundum Type	Ostium Secundum Asd
Osasd	Asd, Ostium Secundum Type
Pfo - [Patent Foramen Ovale]	Open Foramen Ovale
Open Oval Foramen	Persistent Foramen Ovale
Secundum Atrial Septal Defect

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12060	RNF157 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	RNF157	MGD	MGI:2442484
Rattus norvegicus	RNF157	RGD	RGD:1591154
Felis catus	RNF157	VGNC	VGNC:64677
Bos taurus	RNF157	VGNC	VGNC:34031
Macaca mulatta	RNF157	VGNC	VGNC:76860
Canis familiaris	RNF157	VGNC	VGNC:54352

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