2. Gene
  3. OSBPL7 - oxysterol binding protein like 7 Gene

OSBPL7 - oxysterol binding protein like 7 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ORP7

Gene ID: 114881 | Gene type: protein coding

About OSBPL7

Cytogenetic location: 17q21.32 Genomic coordinates (GRCh38): 17:47,807,372-47,821,794 (from NCBI)

This gene has 11 transcripts (splice variants), 274 orthologues and 11 paralogues. Broad expression in stomach (RPKM 18.4), duodenum (RPKM 12.5) and 22 other tissues.

Summary

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008]

OSBPL7 Products(1)

mRNA Protein Name
NM_145798.3 NP_665741.1 oxysterol-binding protein-related protein 7

OSBPL7 Protein Structure

PH_8

PH_8: Pleckstrin homology domain (52 - 138)

Oxysterol_BP

Oxysterol_BP: Oxysterol-binding protein (478 - 826)

  • 0
  • 200
  • 400
  • 600
  • 842 a.a.
Protein Preferred Names Protein Names

oxysterol-binding protein-related protein 7

ORP-7

Related Diseases

Diseases Alias
Opisthorchiasis

Infection By Opisthorchis

Infection Due To Opisthorchis

Infection Due To Cat Liver Fluke

Infection By Cat Liver Fluke

Opisthorchiosis

Cat Liver Fluke Fever

Cat Liver Fluke Disease

Opisthorchis Infestation

Cat Liver Fluke Infestation
Adult Medulloblastoma

Adult Brain Medulloblastoma

Medulloblastoma, Adult
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-143200 OSBPL7-IN-1 99.79% Unkown
HY-RS09844 OSBPL7 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta OSBPL7 VGNC VGNC:75626
Rattus norvegicus OSBPL7 RGD RGD:1309141
Bos taurus OSBPL7 VGNC VGNC:32465
Felis catus OSBPL7 VGNC VGNC:63982
Mus musculus OSBPL7 MGD MGI:1918490
Canis familiaris OSBPL7 VGNC VGNC:44157