1. Gene
  2. OSBPL10 - oxysterol binding protein like 10 Gene

OSBPL10 - oxysterol binding protein like 10 Gene

Homo sapiens

Also known as ORP10; OSBP9

Gene ID: 114884 | Gene type: protein coding

About OSBPL10

Cytogenetic location: 3p23-p22.3 Genomic coordinates (GRCh38): 3:31,660,825-32,077,692 (from NCBI)

This gene has 20 transcripts (splice variants), 251 orthologues and 11 paralogues. Broad expression in testis (RPKM 5.3), placenta (RPKM 5.2) and 23 other tissues.

Summary

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

OSBPL10 Products(2)

mRNA Protein Name
NM_001174060.2 NP_001167531.1 oxysterol-binding protein-related protein 10 isoform 2
NM_017784.5 NP_060254.2 oxysterol-binding protein-related protein 10 isoform 1

OSBPL10 Protein Structure

PH_8

PH_8: Pleckstrin homology domain (85 - 167)

Oxysterol_BP

Oxysterol_BP: Oxysterol-binding protein (401 - 750)

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  • 600
  • 764 a.a.
Protein Preferred Names Protein Names

oxysterol-binding protein-related protein 10

ORP-10

Orthologs Information

Species Symbol Source ID
Mus musculus OSBPL10 MGD MGI:1921736
Bos taurus OSBPL10 VGNC VGNC:32458
Macaca mulatta OSBPL10 VGNC VGNC:75629
Felis catus OSBPL10 VGNC VGNC:63976
Rattus norvegicus OSBPL10 RGD RGD:1561652
Canis familiaris OSBPL10 VGNC VGNC:44151