CMTM5 - CKLF like MARVEL transmembrane domain containing 5 Gene

Homo sapiens

Also known as CKLFSF5

Gene ID: 116173 | Gene type: protein coding

About CMTM5

Cytogenetic location: 14q11.2 Genomic coordinates (GRCh38): 14:23,376,771-23,379,772 (from NCBI)

This gene has 9 transcripts (splice variants), 107 orthologues and 14 paralogues. Biased expression in brain (RPKM 15.6), bone marrow (RPKM 1.3) and 1 other tissue.

Summary

This gene encodes a member of the chemokine-like factor superfamily. This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules. The encoded protein may exhibit tumor suppressor activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

CMTM5 Products(5)

mRNA	Protein	Name
NM_001037288.2	NP_001032365.1	CKLF-like MARVEL transmembrane domain-containing protein 5 isoform c
NM_001288744.2	NP_001275673.1	CKLF-like MARVEL transmembrane domain-containing protein 5 isoform d
NM_001288745.2	NP_001275674.1	CKLF-like MARVEL transmembrane domain-containing protein 5 isoform e
NM_001288746.2	NP_001275675.1	CKLF-like MARVEL transmembrane domain-containing protein 5 isoform f
NM_138460.3	NP_612469.1	CKLF-like MARVEL transmembrane domain-containing protein 5 isoform a

CMTM5 Protein Structure

MARVEL

0
100
200
223 a.a.

Protein Preferred Names

Protein Names

CKLF-like MARVEL transmembrane domain-containing protein 5

chemokine-like factor super family 5

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02867	CMTM5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CMTM5	VGNC	VGNC:39382
Rattus norvegicus	CMTM5	RGD	RGD:1307045
Mus musculus	CMTM5	MGD	MGI:2447164
Felis catus	CMTM5	VGNC	VGNC:61002
Bos taurus	CMTM5	VGNC	VGNC:27485
Macaca mulatta	CMTM5	VGNC	VGNC:71217

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