F2rl3 - F2R like thrombin or trypsin receptor 3 Gene

Rattus norvegicus

Also known as PAR4

Gene ID: 116498 | Gene type: protein coding

About F2rl3

Primary_assembly 16: 17,117,441-17,119,472 reverse strand.mRatBN7.2:CM026989.1

This gene has 1 transcript (splice variant), 194 orthologues, 14 paralogues and is associated with 3 phenotypes. Biased expression in Spleen (RPKM 9.7), Thymus (RPKM 7.4) and 8 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction; positive regulation of cytosolic calcium ion concentration involved in Phospholipase C-activating G protein-coupled signaling pathway; and positive regulation of release of sequestered calcium ion into cytosol. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human F2RL3 (F2R like Thrombin or trypsin receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

F2rl3 Products(1)

mRNA	Protein	Name
NM_053808.1	NP_446260.1	proteinase-activated receptor 4

F2rl3 Protein Structure

7tmA_PAR4

0
100
200
300
386 a.a.

Protein Preferred Names

Protein Names

proteinase-activated receptor 4

F2R like thrombin/trypsin receptor 3	PAR-4
coagulation factor II (thrombin) receptor-like 3	coagulation factor II receptor-like 3
protease-activated receptor 4	thrombin receptor-like 3

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04640	F2RL3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS04641	F2rl3 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS04642	F2rl3 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	F2rl3	NCBI	NCBI:9002

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