1. Gene
  2. GSTO2 - glutathione S-transferase omega 2 Gene

GSTO2 - glutathione S-transferase omega 2 Gene

Homo sapiens

Also known as GSTO 2-2; bA127L20.1

Gene ID: 119391 | Gene type: protein coding

About GSTO2

Cytogenetic location: 10q25.1 Genomic coordinates (GRCh38): 10:104,269,184-104,304,950 (from NCBI)

This gene has 7 transcripts (splice variants), 542 orthologues and 14 paralogues. Broad expression in skin (RPKM 2.1), testis (RPKM 1.8) and 21 other tissues.

Summary

The protein encoded by this gene is an omega class glutathione S-transferase (GST). GSTs are involved in the metabolism of xenobiotics and carcinogens. Four transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]

GSTO2 Products(4)

mRNA Protein Name
NM_001191013.2 NP_001177942.1 glutathione S-transferase omega-2 isoform 2
NM_001191014.2 NP_001177943.1 glutathione S-transferase omega-2 isoform 3
NM_001191015.2 NP_001177944.1 glutathione S-transferase omega-2 isoform 4
NM_183239.2 NP_899062.1 glutathione S-transferase omega-2 isoform 1

GSTO2 Protein Structure

GST_N_3

GST_N_3: Glutathione S-transferase, N-terminal domain (27 - 100)

GST_C_2

GST_C_2: Glutathione S-transferase, C-terminal domain (143 - 204)

  • 0
  • 100
  • 200
  • 243 a.a.
Protein Preferred Names Protein Names

glutathione S-transferase omega-2

GSTO-2

Related Diseases

Diseases Alias
Chronic Closed-Angle Glaucoma

Anatomical Narrow Angle Glaucoma

Chronic Angle-Closure Glaucoma

Chronic Narrow Angle Glaucoma

Secondary Angle-Closure Glaucoma - Synechial

Cataract

Cataracts

Cat - [Cataract]

Cataract Form

Lens Opacity

Lens Opacities

Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris GSTO2 VGNC VGNC:110343
Mus musculus GSTO2 MGD MGI:1915464
Macaca mulatta GSTO2 VGNC VGNC:106055
Bos taurus GSTO2 VGNC VGNC:29687
Felis catus GSTO2 VGNC VGNC:62732
Rattus norvegicus GSTO2 RGD RGD:1310764