CNGA4 - cyclic nucleotide gated channel subunit alpha 4 Gene

Homo sapiens

Also known as CNG4; CNG5; CNCA2; CNG-4; CNGB2; OCNC2; OCNCb; OCNCBETA

Gene ID: 1262 | Gene type: protein coding

About CNGA4

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:6,234,793-6,244,976 (from NCBI)

This gene has 2 transcripts (splice variants), 202 orthologues and 17 paralogues. Biased expression in testis (RPKM 2.8), lung (RPKM 0.7) and 3 other tissues.

Summary

CNGA4 is a modulatory subunit of vertebrate cyclic nucleotide-gated membrane channels that transduce odorant signals (Munger et al., 2001 [PubMed 11739959]).[supplied by OMIM, Mar 2008]

CNGA4 Products(1)

mRNA	Protein	Name
NM_001037329.4	NP_001032406.1	cyclic nucleotide-gated cation channel alpha-4

CNGA4 Protein Structure

Ion_trans

cNMP_binding

0
100
200
300
400
500
575 a.a.

Protein Preferred Names

Protein Names

cyclic nucleotide-gated cation channel alpha-4

CNG channel alpha-4

Related Diseases

Diseases

Alias

Retinitis Pigmentosa 45

RP45	Retinitis Pigmentosa, Type 45

Achromatopsia 3

ACHM3	Pingelapese Blindness
Total Colorblindness With Myopia	Achromatopsia With Myopia
Achm1	Rmch1
Rod Monochromacy 1	Rod Monochromatism 1
Achm1, Formerly	Rod Monochromatism 1, Formerly
Rod Monochromacy 1, Formerly	Rmch1, Formerly
Achromatopsia-3	Achromatopsia, Type 3

Achromatopsia 2

ACHM2	Rod Monochromatism 2
Rod Monochromacy 2	Rmch2
Colorblindness, Total	Complete Achromatopsia
Total Colorblindness	Achromatopsia-2
Achromatopsia, Type 2	Color Blindness
Achromatopsia

Achromatopsia

Achm	Rod Monochromatism
Total Color Blindness	Rod Monochromacy
Monochromatism	Achromatism
Complete Or Incomplete Color Blindness	Pingelapese Blindness
Achromatopsia 1	Achromatopsia 2
Achromatopsia 3

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02882	CNGA4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CNGA4	VGNC	VGNC:61013
Bos taurus	CNGA4	VGNC	VGNC:27500
Rattus norvegicus	CNGA4	RGD	RGD:619844
Canis familiaris	CNGA4	VGNC	VGNC:39397
Macaca mulatta	CNGA4	VGNC	VGNC:82128
Mus musculus	CNGA4	MGD	MGI:2664099
Others	CNGA4	NCBI

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