GABPB2 - GA binding protein transcription factor subunit beta 2 Gene

Homo sapiens

Also known as GABPB-2

Gene ID: 126626 | Gene type: protein coding

About GABPB2

This gene has 6 transcripts (splice variants), 160 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 4.7), ovary (RPKM 3.2) and 25 other tissues.

Summary

Enables transcription cis-regulatory region binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

GABPB2 Products(9)

mRNA	Protein	Name
NM_001323906.2	NP_001310835.1	GA-binding protein subunit beta-2 isoform b
NM_001323907.2	NP_001310836.1	GA-binding protein subunit beta-2 isoform c
NM_001323908.2	NP_001310837.1	GA-binding protein subunit beta-2 isoform a
NM_001323909.2	NP_001310838.1	GA-binding protein subunit beta-2 isoform d
NM_001323910.2	NP_001310839.1	GA-binding protein subunit beta-2 isoform h
NM_001323911.2	NP_001310840.1	GA-binding protein subunit beta-2 isoform e
NM_001323912.2	NP_001310841.1	GA-binding protein subunit beta-2 isoform f
NM_001323913.2	NP_001310842.1	GA-binding protein subunit beta-2 isoform g
NM_144618.3	NP_653219.1	GA-binding protein subunit beta-2 isoform a

GABPB2 Protein Structure

Ank_3

Ank_2

0
100
200
300
400
448 a.a.

Protein Preferred Names

Protein Names

GA-binding protein subunit beta-2

GA binding protein transcription factor beta subunit 2

Related Diseases

Diseases

Alias

Paranoid Schizophrenia

Chronic Paranoid Schizophrenia	Paranoid Type Schizophrenia
Paranoid Type Schizophrenia Subchronic State	Paraphrenia - Late
Paraphrenic Schizophrenia	Schizophrenia, Paranoid

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05208	GABPB2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	GABPB2	VGNC	VGNC:29190
Rattus norvegicus	GABPB2	RGD	RGD:1565234
Macaca mulatta	GABPB2	VGNC	VGNC:72798
Felis catus	GABPB2	VGNC	VGNC:80214
Mus musculus	GABPB2	MGD	MGI:95612
Canis familiaris	GABPB2	VGNC	VGNC:41052

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