CMPK2 - cytidine/uridine monophosphate kinase 2 Gene

Homo sapiens

Also known as NDK; TYKi; TMPK2; UMP-CMPK2

Gene ID: 129607 | Gene type: protein coding

About CMPK2

Cytogenetic location: 2p25.2 Genomic coordinates (GRCh38): 2:6,840,553-6,866,635 (from NCBI)

This gene has 7 transcripts (splice variants), 175 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 6.8), spleen (RPKM 4.2) and 23 other tissues.

Summary

This gene encodes one of the enzymes in the nucleotide synthesis salvage pathway that may participate in terminal differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

CMPK2 Products(3)

mRNA	Protein	Name
NM_001256477.1	NP_001243406.1	UMP-CMP kinase 2, mitochondrial isoform 2 precursor
NM_001256478.1	NP_001243407.1	UMP-CMP kinase 2, mitochondrial isoform 3 precursor
NM_207315.4	NP_997198.2	UMP-CMP kinase 2, mitochondrial isoform 1 precursor

CMPK2 Protein Structure

Thymidylate_kin

0
100
200
300
400
449 a.a.

Protein Preferred Names

Protein Names

UMP-CMP kinase 2, mitochondrial

UMP/CMP kinase

Related Diseases

Diseases

Alias

Neuroaspergillosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02862	CMPK2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	CMPK2	VGNC	VGNC:71362
Mus musculus	CMPK2	MGD	MGI:99830
Rattus norvegicus	CMPK2	RGD	RGD:1305881
Bos taurus	CMPK2	VGNC	VGNC:27481

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