2. Gene
  3. OSR1 - odd-skipped related transcription factor 1 Gene

OSR1 - odd-skipped related transcription factor 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ODD

Gene ID: 130497 | Gene type: protein coding

About OSR1

Cytogenetic location: 2p24.1 Genomic coordinates (GRCh38): 2:19,344,874-19,358,623 (from NCBI)

This gene has 3 transcripts (splice variants), 205 orthologues and 1 paralogue. Broad expression in salivary gland (RPKM 5.4), endometrium (RPKM 5.3) and 19 other tissues.

Summary

Enables sequence-specific double-stranded DNA binding activity. Involved in negative regulation of ion transmembrane transporter activity; positive regulation of gastrulation; and pronephros development. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

OSR1 Products(1)

mRNA Protein Name
NM_145260.3 NP_660303.1 protein odd-skipped-related 1

OSR1 Protein Structure

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (189 - 213)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (217 - 240)

  • 0
  • 100
  • 200
  • 266 a.a.
Protein Preferred Names Protein Names

protein odd-skipped-related 1

odd-skipped homolog

Related Diseases

Diseases Alias
Hydronephrosis

Stricture Of Ureteropelvic Junction With Hydronephrosis

Hydronephrosis With Ureteral Stricture, Not Elsewhere Classified
Wilms Tumor 1

Nephroblastoma

Wilms Tumor

WT1

Wilms' Tumor

Bilateral Wilms Tumor

Wilms Tumor, Type 1

Wilms Tumor, Somatic

Adult Nephroblastoma

Wt1 Disorder

Renal Embryonic Tumor

Adult Kidney Wilms Tumor

Childhood Kidney Wilms Tumor

Nonanaplastic Kidney Wilms Tumor
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-151545 WNK1-IN-1 Inhibitor 99.40% Unkown
HY-RS09852 OSR1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus OSR1 VGNC VGNC:68618
Mus musculus OSR1 MGD MGI:1344424
Bos taurus OSR1 VGNC VGNC:32476
Rattus norvegicus OSR1 RGD RGD:1311807
Canis familiaris OSR1 VGNC VGNC:44168
Others OSR1 NCBI