GRPEL2 - GrpE like 2, mitochondrial Gene

Homo sapiens

Also known as Mt-GrpE#2

Gene ID: 134266 | Gene type: protein coding

About GRPEL2

Cytogenetic location: 5q32 Genomic coordinates (GRCh38): 5:149,345,499-149,354,583 (from NCBI)

This gene has 4 transcripts (splice variants), 170 orthologues and 1 paralogue. Ubiquitous expression in esophagus (RPKM 15.4), fat (RPKM 4.6) and 24 other tissues.

Summary

Predicted to enable adenyl-nucleotide exchange factor activity and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

GRPEL2 Products(1)

mRNA	Protein	Name
NM_152407.4	NP_689620.2	grpE protein homolog 2, mitochondrial precursor

GRPEL2 Protein Structure

GrpE

0
100
200
225 a.a.

Protein Preferred Names

Protein Names

grpE protein homolog 2, mitochondrial

Related Diseases

Diseases

Alias

Freemartinism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05846	GRPEL2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	GRPEL2	VGNC	VGNC:102218
Rattus norvegicus	GRPEL2	RGD	RGD:1585231
Mus musculus	GRPEL2	MGD	MGI:1334416
Canis familiaris	GRPEL2	VGNC	VGNC:41518
Macaca mulatta	GRPEL2	VGNC	VGNC:73208

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