CR1L - complement C3b/C4b receptor 1 like Gene

Homo sapiens

Gene ID: 1379 | Gene type: protein coding

About CR1L

Cytogenetic location: 1q32.2 Genomic coordinates (GRCh38): 1:207,645,133-207,723,703 (from NCBI)

This gene has 5 transcripts (splice variants), 21 orthologues and 39 paralogues. Biased expression in bone marrow (RPKM 3.2), appendix (RPKM 1.6) and 5 other tissues.

Summary

Acts upstream of or within regulation of complement activation and regulation of complement-dependent cytotoxicity. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2022]

CR1L Products(1)

mRNA	Protein	Name
NM_175710.2	NP_783641.1	complement component receptor 1-like protein precursor

CR1L Protein Structure

Sushi

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569 a.a.

Protein Preferred Names

Protein Names

complement component receptor 1-like protein

complement C4b-binding protein CR-1-like protein

Related Diseases

Diseases

Alias

Complement Component Receptor 1

Cortisone Reductase Deficiency

11-Alpha Beta-Hydroxysteroid Dehydrogenase Type I Deficiency Of	Cortrd
Hsd 11b1 Deficiency

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03132	CR1L Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CR1L	RGD	RGD:2399
Mus musculus	CR1L	MGD	MGI:88513