2. Gene
  3. NACC2 - NACC family member 2 Gene

NACC2 - NACC family member 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as RBB; BEND9; NAC-2; BTBD14; BTBD31; BTBD14A

Gene ID: 138151 | Gene type: protein coding

About NACC2

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:136,006,537-136,095,289 (from NCBI)

This gene has 3 transcripts (splice variants), 257 orthologues and 28 paralogues. Ubiquitous expression in brain (RPKM 17.8), fat (RPKM 7.6) and 24 other tissues.

Summary

Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; histone deacetylase binding activity; and protein homodimerization activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; and protein homooligomerization. Located in chromatin; mitochondrion; and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

NACC2 Products(1)

mRNA Protein Name
NM_144653.5 NP_653254.1 nucleus accumbens-associated protein 2

NACC2 Protein Structure

BTB

BTB: BTB/POZ domain (20 - 116)

BEN

BEN: BEN domain (374 - 446)

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  • 587 a.a.
Protein Preferred Names Protein Names

nucleus accumbens-associated protein 2

BEN domain containing 9

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09003 NACC2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris NACC2 VGNC VGNC:43604
Bos taurus NACC2 VGNC VGNC:31862
Rattus norvegicus NACC2 RGD RGD:1309292
Macaca mulatta NACC2 VGNC VGNC:75013
Mus musculus NACC2 MGD MGI:1915241
Felis catus NACC2 VGNC VGNC:63709