ISM1 - isthmin 1 Gene

Homo sapiens

Also known as ISM; Isthmin; C20orf82; bA149I18.1; dJ1077I2.1

Gene ID: 140862 | Gene type: protein coding

About ISM1

Cytogenetic location: 20p12.1 Genomic coordinates (GRCh38): 20:13,221,274-13,326,723 (from NCBI)

This gene has 1 transcript (splice variant), 202 orthologues and 5 paralogues. Biased expression in thyroid (RPKM 10.3), placenta (RPKM 5.3) and 12 other tissues.

Summary

Predicted to be involved in negative regulation of angiogenesis. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

ISM1 Products(1)

mRNA	Protein	Name
NM_080826.2	NP_543016.1	isthmin-1 precursor

ISM1 Protein Structure

TSP_1

AMOP

0
100
200
300
400
464 a.a.

Protein Preferred Names

Protein Names

isthmin-1

isthmin 1 homolog

Recombinant ISM1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P79426	ISM1 Protein, Human (CHO, His)	B1AKI9 (S27-Y464)	≥95%

Related Diseases

Diseases

Alias

Non-Syndromic X-Linked Intellectual Disability 14

Mrx14

Cancerophobia

Cancer Phobia

Fear Of Getting Cancer

Nosophobia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06935	ISM1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ISM1	VGNC	VGNC:42111
Bos taurus	ISM1	VGNC	VGNC:30300
Rattus norvegicus	ISM1	RGD	RGD:1562551
Macaca mulatta	ISM1	VGNC	VGNC:73607
Felis catus	ISM1	VGNC	VGNC:62976
Mus musculus	ISM1	MGD	MGI:2442963

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