1. Gene
  2. COMMD7 - COMM domain containing 7 Gene

COMMD7 - COMM domain containing 7 Gene

Homo sapiens

Also known as C20orf92; dJ1085F17.3

Gene ID: 149951 | Gene type: protein coding

About COMMD7

Cytogenetic location: 20q11.21 Genomic coordinates (GRCh38): 20:32,702,699-32,743,467 (from NCBI)

This gene has 4 transcripts (splice variants), 206 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 17.9), placenta (RPKM 13.5) and 25 other tissues.

Summary

Enables NF-kappaB binding activity. Involved in negative regulation of NF-kappaB transcription factor activity; negative regulation of transcription, DNA-templated; and tumor necrosis factor-mediated signaling pathway. Predicted to be located in cytoplasmic vesicle. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

COMMD7 Products(2)

mRNA Protein Name
NM_001099339.2 NP_001092809.1 COMM domain-containing protein 7 isoform 2
NM_053041.3 NP_444269.2 COMM domain-containing protein 7 isoform 1

COMMD7 Protein Structure

COMM_domain

COMM_domain: COMM domain (20 - 198)

  • 0
  • 100
  • 200 a.a.
Protein Preferred Names Protein Names

COMM domain-containing protein 7

Orthologs Information

Species Symbol Source ID
Bos taurus COMMD7 VGNC VGNC:27587
Canis familiaris COMMD7 VGNC VGNC:39497
Rattus norvegicus COMMD7 RGD RGD:1307786
Macaca mulatta COMMD7 VGNC VGNC:81182
Mus musculus COMMD7 MGD MGI:1914197