1. Gene
  2. SLC2A12 - solute carrier family 2 member 12 Gene

SLC2A12 - solute carrier family 2 member 12 Gene

Homo sapiens

Also known as GLUT8; GLUT12

Gene ID: 154091 | Gene type: protein coding

About SLC2A12

Cytogenetic location: 6q23.2 Genomic coordinates (GRCh38): 6:133,987,581-134,052,624 (from NCBI)

This gene has 1 transcript (splice variant), 289 orthologues and 13 paralogues. Broad expression in prostate (RPKM 9.5), endometrium (RPKM 4.6) and 18 other tissues.

Summary

SLC2A12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Rogers et al., 2002). This family of transporters show conservation of 12 transmembrane helices as well as functionally significant amino acid residues (Joost and Thorens, 2001 [PubMed 11780753]).[supplied by OMIM, Mar 2008]

SLC2A12 Products(1)

mRNA Protein Name
NM_145176.3 NP_660159.1 solute carrier family 2, facilitated glucose transporter member 12

SLC2A12 Protein Structure

Sugar_tr

Sugar_tr: Sugar (and other) transporter (45 - 365)

Sugar_tr

Sugar_tr: Sugar (and other) transporter (462 - 562)

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  • 617 a.a.
Protein Preferred Names Protein Names

solute carrier family 2, facilitated glucose transporter member 12

GLUT-12

Related Diseases

Diseases Alias
Arterial Tortuosity Syndrome

Arterial Tortuosity

Ats

ATORS

Tortuosity, Arterial, Syndrome

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus SLC2A12 VGNC VGNC:34798
Mus musculus SLC2A12 MGD MGI:3052471
Rattus norvegicus SLC2A12 RGD RGD:1310175
Felis catus SLC2A12 VGNC VGNC:65301
Macaca mulatta SLC2A12 VGNC VGNC:77503
Canis familiaris SLC2A12 VGNC VGNC:46339