2. Gene
  3. RASEF - RAS and EF-hand domain containing Gene

RASEF - RAS and EF-hand domain containing Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TSG; RAB45

Gene ID: 158158 | Gene type: protein coding

About RASEF

Cytogenetic location: 9q21.32 Genomic coordinates (GRCh38): 9:82,979,590-83,219,224 (from NCBI)

This gene has 2 transcripts (splice variants), 201 orthologues and 68 paralogues. Broad expression in stomach (RPKM 15.4), thyroid (RPKM 14.0) and 15 other tissues.

Summary

This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene. [provided by RefSeq, Nov 2012]

RASEF Products(1)

mRNA Protein Name
NM_152573.4 NP_689786.2 ras and EF-hand domain-containing protein

RASEF Protein Structure

EF-hand_7

EF-hand_7: EF-hand domain pair (12 - 69)

Ras

Ras: Ras family (543 - 709)

  • 0
  • 200
  • 400
  • 600
  • 740 a.a.
Protein Preferred Names Protein Names

ras and EF-hand domain-containing protein

ras-related protein Rab-45

Related Diseases

Diseases Alias
Cutaneous Adenocystic Carcinoma

Adenoid Cystic Eccrine Carcinoma

Adenoid Cystic Carcinoma Of The Skin

Adenoid Cystic Eccrine Carcinoma Of Skin
Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11687 RASEF Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RASEF RGD RGD:1306418
Canis familiaris RASEF VGNC VGNC:45366
Bos taurus RASEF VGNC VGNC:33742
Macaca mulatta RASEF VGNC VGNC:82089
Felis catus RASEF VGNC VGNC:64499
Mus musculus RASEF MGD MGI:2448565