2. Gene
  3. GPR180 - G protein-coupled receptor 180 Gene

GPR180 - G protein-coupled receptor 180 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ITR

Gene ID: 160897 | Gene type: protein coding

About GPR180

Cytogenetic location: 13q32.1 Genomic coordinates (GRCh38): 13:94,601,857-94,634,661 (from NCBI)

This gene has 1 transcript (splice variant), 205 orthologues and 1 paralogue. Ubiquitous expression in fat (RPKM 4.6), thyroid (RPKM 2.7) and 25 other tissues.

Summary

This gene encodes a protein that is a member of the G protein-coupled receptor superfamily. This protein is produced predominantly in vascular smooth muscle cells and may play an important role in the regulation of vascular remodeling. [provided by RefSeq, Jul 2008]

GPR180 Products(1)

mRNA Protein Name
NM_180989.6 NP_851320.1 integral membrane protein GPR180 precursor

GPR180 Protein Structure

GpcrRhopsn4

GpcrRhopsn4: Rhodopsin-like GPCR transmembrane domain (143 - 405)

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  • 440 a.a.
Protein Preferred Names Protein Names

integral membrane protein GPR180

intimal thickness-related receptor

Related Diseases

Diseases Alias
Bladder Neck Obstruction

Obstruction Of Bladder Neck Or Vesicourethral Orifice

Urinary Bladder Neck Obstruction

Bladder Outlet Obstruction

Vesicourethral Orifice Obstruction

Bno - [Bladder Neck Obstruction]

Bladder Obstruction Nos

Acquired Bladder Neck Obstruction

Acquired Obstruction Of Bladder Neck Or Vesicourethral Orifice

Bladder Neck Strangulation

Bladder Neck Stricture

Bladder Outflow Obstruction

Contracture Of Bladder Neck Or Sphincter

Contracture Of Bladder Neck

Obstructed Vesicourethral Orifice

Strangulation Of Vesicourethral Orifice

Stricture Of Vesicourethral Orifice

Urinary Prostatic Valve Obstruction

Vesical Obstruction
Juvenile Glaucoma

Glaucoma Of Childhood

Hydrophthalmos
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05688 GPR180 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus GPR180 RGD RGD:1359193
Felis catus GPR180 VGNC VGNC:62690
Mus musculus GPR180 MGD MGI:1930949
Canis familiaris GPR180 VGNC VGNC:41421
Bos taurus GPR180 VGNC VGNC:29575
Macaca mulatta GPR180 VGNC VGNC:103822