2. Gene
  3. DDT - D-dopachrome tautomerase Gene

DDT - D-dopachrome tautomerase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as D-DT; DDCT; MIF2; MIF-2

Gene ID: 1652 | Gene type: protein coding

About DDT

Cytogenetic location: 22q11.23 Genomic coordinates (GRCh38): 22:23,971,370-23,980,504 (from NCBI)

This gene has 8 transcripts (splice variants), 1 gene allele, 174 orthologues and 2 paralogues. Broad expression in liver (RPKM 108.4), kidney (RPKM 65.2) and 23 other tissues.

Summary

D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. The DDT gene is related to the migration inhibitory factor (MIF) in terms of sequence, Enzyme activity, and gene structure. DDT and MIF are closely linked on chromosome 22. [provided by RefSeq, Jul 2008]

DDT Products(4)

mRNA Protein Name
NM_001084392.3 NP_001077861.1 D-dopachrome decarboxylase isoform a
NM_001355.4 NP_001346.1 D-dopachrome decarboxylase isoform a
NM_001381852.2 NP_001368781.1 D-dopachrome decarboxylase isoform b
NM_001397485.1 NP_001384414.1 D-dopachrome decarboxylase isoform a

DDT Protein Structure

MIF

MIF: Macrophage migration inhibitory factor (MIF) (2 - 116)

  • 0
  • 100
  • 118 a.a.
Protein Preferred Names Protein Names

D-dopachrome decarboxylase

phenylpyruvate tautomerase II

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13690 Mitotane Inducer 99.94% Yes
Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1984 p,p'-DDD 99.71% Unkown
HY-B1986 p,p'-DDE Antagonist 99.50% Unkown
HY-B1970S 2,4'-DDT-d8 / Unkown
HY-13690S1 Mitotane-13C6 / Unkown
HY-13690S2 Mitotane-d8 / Unkown
HY-B1873S Methoxychlor-d6 / Unkown
HY-B1984S p,p'-DDD-d8 / Unkown
HY-B1986S p,p'-DDE-d8 / Unkown
HY-RS03627 DDT Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-122551 Chlorfenethol / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus DDT RGD RGD:61923
Mus musculus DDT MGD MGI:1298381