2. Gene
  3. KCNG3 - potassium voltage-gated channel modifier subfamily G member 3 Gene

KCNG3 - potassium voltage-gated channel modifier subfamily G member 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as KV6.3; KV10.1

Gene ID: 170850 | Gene type: protein coding

About KCNG3

Cytogenetic location: 2p21 Genomic coordinates (GRCh38): 2:42,388,352-42,493,982 (from NCBI)

This gene has 2 transcripts (splice variants), 182 orthologues and 31 paralogues. Low expression observed in reference dataset.

Summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, Insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the Potassium Channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

KCNG3 Products(2)

mRNA Protein Name
NM_133329.6 NP_579875.1 potassium voltage-gated channel subfamily G member 3 isoform 1
NM_172344.3 NP_758847.1 potassium voltage-gated channel subfamily G member 3 isoform 2

KCNG3 Protein Structure

BTB_2

BTB_2: BTB/POZ domain (11 - 111)

Ion_trans

Ion_trans: Ion transport protein (223 - 408)

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  • 436 a.a.
Protein Preferred Names Protein Names

potassium voltage-gated channel subfamily G member 3

potassium channel, voltage gated modifier subfamily G, member 3

Related Diseases

Diseases Alias
Retinal Cone Dystrophy 3b

RCD3B

Cone Dystrophy With Supernormal Rod Response

Cone Dystrophy With Supernormal Rod Electroretinogram

Cone Dystrophy With Supernormal Rod Responses

Cdsrr

Cone Dystrophy With Night Blindness And Supernormal Rod Responses, Kcnv2-Related

Cone Dystrophy With Night Blindness And Supernormal Rod Responses Kcnv2 Related

Cone Dystrophy With Supernormal Rod Erg

Cone Dystrophy With Supernormal Scotopic Electroretinogram

Cone Dystrophy Retinal 3b

Cone Dystrophy With Night Blindness And Supernormal Rod Responses Kcnv2-Related

Doid:0081022

Dystrophy, Retinal Cone, Type 3b
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07123 KCNG3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris KCNG3 VGNC VGNC:42246
Rattus norvegicus KCNG3 RGD RGD:628832
Bos taurus KCNG3 VGNC VGNC:58383
Macaca mulatta KCNG3 VGNC VGNC:106175
Mus musculus KCNG3 MGD MGI:2663923