2. Gene
  3. Prkcg - protein kinase C, gamma Gene

Prkcg - protein kinase C, gamma Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Pkcc; Prkcc; PKCgamma

Gene ID: 18752 | Gene type: protein coding

About Prkcg

Chromosome 7: 3,337,704-3,379,615 forward strand.GRCm39:CM001000.3

This gene has 5 transcripts (splice variants), 201 orthologues, 9 paralogues and is associated with 13 phenotypes. Biased expression in cerebellum adult (RPKM 34.3), frontal lobe adult (RPKM 31.8) and 5 other tissues.

Summary

Predicted to enable calcium-dependent protein kinase C activity and protein serine/threonine/tyrosine kinase activity. Involved in several processes, including modulation of chemical synaptic transmission; negative regulation of cellular protein metabolic process; and response to morphine. Acts upstream of or within chemosensory behavior and regulation of phagocytosis. Located in several cellular components, including calyx of Held; postsynaptic density; and synaptic membrane. Is active in presynaptic cytosol. Is expressed in several structures, including alimentary system; central nervous system; early embryo; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 14. Orthologous to human PRKCG (protein kinase C gamma). [provided by Alliance of Genome Resources, Apr 2022]

Prkcg Products(2)

mRNA Protein Name
NM_001291434.1 NP_001278363.1 protein kinase C gamma type isoform 2
NM_011102.4 NP_035232.1 protein kinase C gamma type isoform 1

Prkcg Protein Structure

C1_cPKC_rpt1

C1_cPKC_rpt1: cd20833 (33 - 90)

C1_cPKC_rpt2

C1_cPKC_rpt2: cd20836 (100 - 153)

C2_PKC_alpha_gamma

C2_PKC_alpha_gamma: cd04026 (157 - 288)

STKc_cPKC

STKc_cPKC: cd05587 (353 - 676)

  • 0
  • 200
  • 400
  • 600
  • 697 a.a.
Protein Preferred Names Protein Names

protein kinase C gamma type

PKC-gamma

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11128 PRKCG Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS11129 Prkcg Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS11130 Prkcg Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prkcg NCBI NCBI:5582