2. Gene
  3. GPR183 - G protein-coupled receptor 183 Gene

GPR183 - G protein-coupled receptor 183 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as EBI2; hEBI2

Gene ID: 1880 | Gene type: protein coding

About GPR183

Cytogenetic location: 13q32.3 Genomic coordinates (GRCh38): 13:99,294,539-99,307,399 (from NCBI)

This gene has 1 transcript (splice variant), 207 orthologues and 7 paralogues. Broad expression in appendix (RPKM 44.7), bone marrow (RPKM 34.8) and 17 other tissues.

Summary

This gene was identified by the up-regulation of its expression upon Epstein-Barr virus Infection of primary B lymphocytes. This gene is predicted to encode a G protein-coupled receptor that is most closely related to the Thrombin receptor. Expression of this gene was detected in B-lymphocyte cell lines and lymphoid tissues but not in T-lymphocyte cell lines or peripheral blood T lymphocytes. The function of this gene is unknown. [provided by RefSeq, Jul 2008]

GPR183 Products(1)

mRNA Protein Name
NM_004951.5 NP_004942.1 G-protein coupled receptor 183

GPR183 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (48 - 308)

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  • 361 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 183

EBV-induced G-protein coupled receptor 2

Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor)

epstein-Barr virus-induced G-protein coupled receptor 2

Related Diseases

Diseases Alias
Bile Acid Synthesis Defect, Congenital, 3

Congenital Bile Acid Synthesis Defect 3

CBAS3

Oxysterol 7-Alpha-Hydroxylase Deficiency

Congenital Bile Acid Synthesis Defect Type 3

Basd3

Bile Acid Synthesis Defect, Congenital, Type 3
Congenital Bile Acid Synthesis Defect

3-Beta-Hydroxy-Delta-5-C27-Steroid Oxidoreductase Deficiency

Cba

Cholestasis With Delta(4)-3-Oxosteroid-5-Beta-Reductase Deficiency

Basd

Bile Acid Synthesis Defect, Congenital, 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-113962 7α,25-Dihydroxycholesterol Agonist ≥99.0% Unkown
HY-147222 SAE-14 Antagonist 98.26% Unkown
HY-162011 GPR183 antagonist-2 Antagonist 99.96% Unkown
HY-113962S 7α,25-Dihydroxycholesterol-d6 / Unkown
HY-157939 GPR183 antagonist-3 Antagonist / Unkown
HY-RS05690 GPR183 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS05691 Gpr183 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS05692 Gpr183 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-400897 7α,25-Dihydroxycholesterol intermediate-1 / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta GPR183 VGNC VGNC:73042
Rattus norvegicus GPR183 RGD RGD:1598095
Mus musculus GPR183 MGD MGI:2442034
Canis familiaris GPR183 VGNC VGNC:41423
Bos taurus GPR183 VGNC VGNC:29577