2. Gene
  3. CENPX - centromere protein X Gene

CENPX - centromere protein X Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as D9; MHF2; CENP-X; FAAP10; STRA13

Gene ID: 201254 | Gene type: protein coding

About CENPX

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:82,018,703-82,022,878 (from NCBI)

This gene has 11 transcripts (splice variants) and 139 orthologues. Ubiquitous expression in prostate (RPKM 17.1), colon (RPKM 14.3) and 25 other tissues.

Summary

Enables DNA binding activity. Contributes to double-stranded DNA binding activity. Involved in replication fork processing and resolution of meiotic recombination intermediates. Part of FANCM-MHF complex and Fanconi anaemia nuclear complex. [provided by Alliance of Genome Resources, Apr 2022]

CENPX Products(4)

mRNA Protein Name
NM_001271006.2 NP_001257935.1 centromere protein X isoform 1
NM_001271007.2 NP_001257936.1 centromere protein X isoform 3
NM_001330536.2 NP_001317465.1 centromere protein X isoform 4
NM_144998.4 NP_659435.2 centromere protein X isoform 2

CENPX Protein Structure

CENP-X

CENP-X: CENP-S associating Centromere protein X (12 - 81)

  • 0
  • 81 a.a.
Protein Preferred Names Protein Names

centromere protein X

FANCM associated histone fold protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02495 CENPX Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CENPX MGD MGI:894324
Rattus norvegicus CENPX RGD RGD:1590057
Macaca mulatta CENPX VGNC VGNC:70934
Bos taurus CENPX VGNC VGNC:27188