2. Gene
  3. Slc2a1 - solute carrier family 2 (facilitated glucose transporter), member 1 Gene

Slc2a1 - solute carrier family 2 (facilitated glucose transporter), member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Glut1; Glut-1; M100200; Rgsc200

Gene ID: 20525 | Gene type: protein coding

About Slc2a1

Chromosome 4: 118,965,908-118,995,180 forward strand.GRCm39:CM000997.3

This gene has 5 transcripts (splice variants), 374 orthologues, 11 paralogues and is associated with 12 phenotypes. Broad expression in liver E14.5 (RPKM 161.1), placenta adult (RPKM 14.1) and 25 other tissues.

Summary

Enables D-glucose transmembrane transporter activity and dehydroascorbic acid transmembrane transporter activity. Involved in dehydroascorbic acid transport and glucose transmembrane transport. Acts upstream of or within cellular response to glucose starvation. Located in several cellular components, including basolateral plasma membrane; female pronucleus; and photoreceptor inner segment. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in brain disease (multiple); carbohydrate metabolic disorder; myelomeningocele; obesity; and type 2 diabetes mellitus. Orthologous to human SLC2A1 (solute carrier family 2 member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slc2a1 Products(1)

mRNA Protein Name
NM_011400.3 NP_035530.2 solute carrier family 2, facilitated glucose transporter member 1

Slc2a1 Protein Structure

MFS_GLUT_Class1

MFS_GLUT_Class1: cd17431 (13 - 457)

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  • 492 a.a.
Protein Preferred Names Protein Names

solute carrier family 2, facilitated glucose transporter member 1

GT1

glucose transporter type 1, erythrocyte/brain

solute carrier family 2, member 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13157 SLC2A1 Human Pre-designed siRNA Set A / Unkown
HY-RS13158 Slc2a1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS13159 Slc2a1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc2a1 NCBI NCBI:6513