2. Gene
  3. SLC37A2 - solute carrier family 37 member 2 Gene

SLC37A2 - solute carrier family 37 member 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SPX2; pp11662

Gene ID: 219855 | Gene type: protein coding

About SLC37A2

Cytogenetic location: 11q24.2 Genomic coordinates (GRCh38): 11:125,063,305-125,090,516 (from NCBI)

This gene has 6 transcripts (splice variants), 241 orthologues and 12 paralogues. Broad expression in adrenal (RPKM 13.0), salivary gland (RPKM 12.4) and 18 other tissues.

Summary

Enables glucose 6-phosphate:inorganic phosphate antiporter activity. Involved in glucose-6-phosphate transport and phosphate ion transmembrane transport. Is integral component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC37A2 Products(2)

mRNA Protein Name
NM_001145290.2 NP_001138762.1 glucose-6-phosphate exchanger SLC37A2 isoform 2
NM_198277.3 NP_938018.1 glucose-6-phosphate exchanger SLC37A2 isoform 1

SLC37A2 Protein Structure

MFS_1

MFS_1: Major Facilitator Superfamily (92 - 414)

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  • 501 a.a.
Protein Preferred Names Protein Names

glucose-6-phosphate exchanger SLC37A2

solute carrier family 37 (glucose-6-phosphate transporter), member 2

Related Diseases

Diseases Alias
Caffey Disease

Infantile Cortical Hyperostosis

CAFYD

Cortical Congenital Hyperostosis

Caffey-Silverman Syndrome

De Toni-Caffey Disease

Hyperostosis Cortical Infantile

Hyperostosis, Cortical, Congenital
Van Den Ende-Gupta Syndrome

VDEGS

Blepharophimosis, Arachnodactyly, And Congenital Contractures

Marden-Walker-Like Syndrome

Marden-Walker-Like Syndrome Without Psychomotor Retardation

Marden Walker Like Syndrome

Marden-Walker-Like Syndrome Without Psychmotor Retardation

Van Den Ende Gupta Syndrome

Marden Walker Like Syndrome Without Psychomotor Retardation

Blepharophimosis Arachnodactyly And Congenital Contractures
Combined Oxidative Phosphorylation Deficiency 24

COXPD24

Combined Oxidative Phosphorylation Defect Type 24

Oxidative Phosphorylation Deficiency, Combined, Type 24
Combined Oxidative Phosphorylation Deficiency 20

COXPD20

Combined Oxidative Phosphorylation Defect Type 20

Oxidative Phosphorylation Deficiency, Combined, Type 20
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-119384 Promegestone Agonist ≥98.0% Unkown
HY-RS13214 SLC37A2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SLC37A2 VGNC VGNC:34843
Mus musculus SLC37A2 MGD MGI:1929693
Macaca mulatta SLC37A2 VGNC VGNC:107645
Felis catus SLC37A2 VGNC VGNC:81937
Canis familiaris SLC37A2 VGNC VGNC:46387
Rattus norvegicus SLC37A2 RGD RGD:1564160