MPEG1 - macrophage expressed 1 Gene

Homo sapiens

Also known as P-2; MPG1; MPS1; IMD77; Mpg-1

Gene ID: 219972 | Gene type: protein coding

About MPEG1

Cytogenetic location: 11q12.1 Genomic coordinates (GRCh38): 11:59,208,510-59,212,927 (from NCBI)

This gene has 1 transcript (splice variant), 237 orthologues and is associated with 1 phenotype.

Summary

Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Located in cytoplasmic vesicle. Implicated in primary immunodeficiency disease. [provided by Alliance of Genome Resources, Apr 2022]

MPEG1 Products(1)

mRNA	Protein	Name
NM_001039396.2	NP_001034485.1	macrophage-expressed gene 1 protein precursor

MPEG1 Protein Structure

MACPF

0
200
400
600
716 a.a.

Protein Preferred Names

Protein Names

macrophage-expressed gene 1 protein

macrophage expressed gene 1

Related Diseases

Diseases

Alias

Immunodeficiency 77

IMD77

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-114512	m-PEG1-NHS ester		≥95.0%	Unkown
HY-RS08610	MPEG1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	MPEG1	VGNC	VGNC:101354
Rattus norvegicus	MPEG1	RGD	RGD:69275
Felis catus	MPEG1	VGNC	VGNC:63570
Canis familiaris	MPEG1	VGNC	VGNC:43333
Mus musculus	MPEG1	MGD	MGI:1333743

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