OTUD1 - OTU deubiquitinase 1 Gene

Homo sapiens

Also known as DUBA7; OTDC1

Gene ID: 220213 | Gene type: protein coding

About OTUD1

Cytogenetic location: 10p12.2 Genomic coordinates (GRCh38): 10:23,439,075-23,442,377 (from NCBI)

This gene has 1 transcript (splice variant), 156 orthologues and 5 paralogues.

Summary

Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. DUBA7 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM, May 2008]

OTUD1 Products(1)

mRNA	Protein	Name
NM_001145373.3	NP_001138845.1	OTU domain-containing protein 1

OTUD1 Protein Structure

OTU

0
100
200
300
400
481 a.a.

Protein Preferred Names

Protein Names

OTU domain-containing protein 1

DUBA-7

Related Diseases

Diseases

Alias

Acquired Hyperkeratosis

Acquired Keratoderma	Keratoderma - Acquired
Keratoderma, Acquired	Keratosis Blennorrhagica

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09871	OTUD1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	OTUD1	VGNC	VGNC:75685
Canis familiaris	OTUD1	VGNC	VGNC:44184
Mus musculus	OTUD1	MGD	MGI:1918448
Rattus norvegicus	OTUD1	RGD	RGD:1563344
Bos taurus	OTUD1	VGNC	VGNC:32493

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