2. Gene
  3. FCER1G - Fc epsilon receptor Ig Gene

FCER1G - Fc epsilon receptor Ig Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FCRG

Gene ID: 2207 | Gene type: protein coding

About FCER1G

Cytogenetic location: 1q23.3 Genomic coordinates (GRCh38): 1:161,215,295-161,219,245 (from NCBI)

This gene has 3 transcripts (splice variants) and 106 orthologues. Broad expression in appendix (RPKM 140.4), spleen (RPKM 128.5) and 19 other tissues.

Summary

The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc Receptors. [provided by RefSeq, Jul 2008]

FCER1G Products(1)

mRNA Protein Name
NM_004106.2 NP_004097.1 high affinity immunoglobulin epsilon receptor subunit gamma precursor

FCER1G Protein Structure

TCR_zetazeta

TCR_zetazeta: T-cell surface glycoprotein CD3 zeta chain (21 - 52)

ITAM

ITAM: Immunoreceptor tyrosine-based activation motif (62 - 81)

  • 0
  • 86 a.a.
Protein Preferred Names Protein Names

high affinity immunoglobulin epsilon receptor subunit gamma

Fc fragment of IgE receptor Ig

Related Diseases

Diseases Alias
Bleeding Disorder, Platelet-Type, 11

BDPLT11

Glycoprotein Vi Deficiency

Gp Vi Deficiency

Platelet-Type Bleeding Disorder 11

Bleeding Diathesis Due To A Collagen Receptor Defect

Bleeding Diathesis Due To Glycoprotein Vi Deficiency

Platelet-Type Bleeding Disorder-11

Bleeding Disorder, Platelet Type 11

Hemorrhage
Malignant Iris Melanoma

Malignant Melanoma Of Iris

Melanoma Of The Iris
Vernal Conjunctivitis

Conjunctivitis Vernal

Conjunctivitis, Vernal
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04823 FCER1G Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus FCER1G VGNC VGNC:28931
Felis catus FCER1G VGNC VGNC:107872
Mus musculus FCER1G MGD MGI:95496
Rattus norvegicus FCER1G RGD RGD:2599
Macaca mulatta FCER1G VGNC VGNC:72629
Canis familiaris FCER1G VGNC VGNC:40802