NID2 - nidogen 2 Gene

Homo sapiens

Also known as NID-2

Gene ID: 22795 | Gene type: protein coding

About NID2

Cytogenetic location: 14q22.1 Genomic coordinates (GRCh38): 14:52,004,809-52,069,059 (from NCBI)

This gene has 7 transcripts (splice variants), 210 orthologues and 14 paralogues. Broad expression in placenta (RPKM 30.5), thyroid (RPKM 21.7) and 16 other tissues.

Summary

This gene encodes a member of the nidogen family of basement membrane proteins. This protein is a cell-adhesion protein that binds collagens I and IV and laminin and may be involved in maintaining the structure of the basement membrane.[provided by RefSeq, Jun 2010]

NID2 Products(1)

mRNA	Protein	Name
NM_007361.4	NP_031387.3	nidogen-2 precursor

NID2 Protein Structure

NIDO

G2F

EGF_CA

cEGF

EGF_3

Thyroglobulin_1

Ldl_recept_b

0
300
600
900
1200
1375 a.a.

Protein Preferred Names

Protein Names

nidogen-2

osteonidogen

Recombinant NID2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P79129	Nidogen-2 Protein, Human (G832A, CHO, His)	Q14112 (L31-K1375, G832A)	≥95%

Related Diseases

Diseases

Alias

Myasthenic Syndrome, Congenital, 19

Congenital Myasthenic Syndrome 19	CMS19
Myasthenic Syndrome, Congenital, Type 19

Clivus Chordoma

Chordoma Of Clivus

Porencephaly

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09295	NID2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	NID2	MGD	MGI:1298229
Canis familiaris	NID2	VGNC	VGNC:59037
Macaca mulatta	NID2	VGNC	VGNC:75165
Bos taurus	NID2	VGNC	VGNC:32074
Rattus norvegicus	NID2	RGD	RGD:1311685