2. Gene
  3. CPEB3 - cytoplasmic polyadenylation element binding protein 3 Gene

CPEB3 - cytoplasmic polyadenylation element binding protein 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 22849 | Gene type: protein coding

About CPEB3

Cytogenetic location: 10q23.32 Genomic coordinates (GRCh38): 10:92,046,692-92,291,233 (from NCBI)

This gene has 3 transcripts (splice variants), 201 orthologues, 3 paralogues and is associated with 68 phenotypes. Broad expression in brain (RPKM 4.8), liver (RPKM 4.1) and 25 other tissues.

Summary

Enables mRNA 3'-UTR binding activity and translation factor activity, RNA binding. Involved in cellular response to amino acid stimulus; negative regulation of transcription by RNA polymerase II; and positive regulation of mRNA catabolic process. Located in several cellular components, including cytosol; midbody; and nucleoplasm. Part of CCR4-NOT complex. [provided by Alliance of Genome Resources, Apr 2022]

CPEB3 Products(2)

mRNA Protein Name
NM_001178137.2 NP_001171608.1 cytoplasmic polyadenylation element-binding protein 3 isoform 2
NM_014912.5 NP_055727.3 cytoplasmic polyadenylation element-binding protein 3 isoform 1

CPEB3 Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (443 - 504)

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  • 698 a.a.
Protein Preferred Names Protein Names

cytoplasmic polyadenylation element-binding protein 3

CPE-BP3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03093 CPEB3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CPEB3 VGNC VGNC:71449
Mus musculus CPEB3 MGD MGI:2443075
Canis familiaris CPEB3 VGNC VGNC:39553
Bos taurus CPEB3 VGNC VGNC:27649
Rattus norvegicus CPEB3 RGD RGD:1564670