2. Gene
  3. MSRB2 - methionine sulfoxide reductase B2 Gene

MSRB2 - methionine sulfoxide reductase B2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CBS1; MSRB; PILB; CBS-1; CGI-131

Gene ID: 22921 | Gene type: protein coding

About MSRB2

Cytogenetic location: 10p12.2 Genomic coordinates (GRCh38): 10:23,095,579-23,122,013 (from NCBI)

This gene has 3 transcripts (splice variants), 101 orthologues and 3 paralogues. Ubiquitous expression in heart (RPKM 17.2), liver (RPKM 8.9) and 24 other tissues.

Summary

Predicted to enable actin binding activity; peptide-methionine (R)-S-oxide reductase activity; and zinc ion binding activity. Predicted to be involved in actin filament polymerization and protein repair. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MSRB2 Products(1)

mRNA Protein Name
NM_012228.4 NP_036360.3 methionine-R-sulfoxide reductase B2, mitochondrial precursor

MSRB2 Protein Structure

SelR

SelR: SelR domain (52 - 179)

  • 0
  • 100
  • 182 a.a.
Protein Preferred Names Protein Names

methionine-R-sulfoxide reductase B2, mitochondrial

pilin-like transcription factor

Related Diseases

Diseases Alias
Hypomagnesemia 6, Renal

Renal Hypomagnesemia 6

HOMG6

Renal Hypomagnesemia-6

Hypomagnesemia 6

Hypomagnesemia, Type 6, Renal
Neu-Laxova Syndrome 2

NLS2
Myotonia Congenita

Congenital Myotonia, Autosomal Dominant Form

Congenital Myotonia

Thomsen And Becker Disease

Thomsen Disease

Thomsen'S Disease

Generalized Myotonia Of Thomsen

Congenital Myotonic Muscular Dystrophy

Myotonia Congenita Nos
Atrial Septal Defect 1

ASD1

Atrial Heart Septal Defect 1

Asd
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08727 MSRB2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta MSRB2 VGNC VGNC:74786
Bos taurus MSRB2 VGNC VGNC:31706
Rattus norvegicus MSRB2 RGD RGD:1306026
Mus musculus MSRB2 MGD MGI:1923717
Canis familiaris MSRB2 VGNC VGNC:43450