FLOT2 - flotillin 2 Gene

Homo sapiens

Also known as ESA; ECS1; ESA1; ECS-1; M17S1

Gene ID: 2319 | Gene type: protein coding

About FLOT2

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:28,879,339-28,897,733 (from NCBI)

This gene has 12 transcripts (splice variants), 279 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 42.8), spleen (RPKM 42.2) and 25 other tissues.

Summary

Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in Neuronal Signaling. [provided by RefSeq, Jul 2008]

FLOT2 Products(2)

mRNA	Protein	Name
NM_001330170.2	NP_001317099.1	flotillin-2 isoform 2
NM_004475.3	NP_004466.2	flotillin-2 isoform 1

FLOT2 Protein Structure

Band_7

0
100
200
300
400
428 a.a.

Protein Preferred Names

Protein Names

flotillin-2

Flotillin 2 (epidermal surface antigen 1)

Related Diseases

Diseases

Alias

Melanoma

Malignant Melanoma	Cutaneous Melanoma
Naevocarcinoma	Malignant Melanomas

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04983	FLOT2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	FLOT2	RGD	RGD:70993
Mus musculus	FLOT2	MGD	MGI:103309
Bos taurus	FLOT2	VGNC	VGNC:29037
Felis catus	FLOT2	VGNC	VGNC:62295

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