IQCE - IQ motif containing E Gene

Homo sapiens

Also known as PAPA7; 1700028P05Rik

Gene ID: 23288 | Gene type: protein coding

About IQCE

Cytogenetic location: 7p22.3 Genomic coordinates (GRCh38): 7:2,558,979-2,614,728 (from NCBI)

This gene has 17 transcripts (splice variants), 69 orthologues, 1 paralogue and is associated with 2 phenotypes. Broad expression in testis (RPKM 11.3), brain (RPKM 6.8) and 24 other tissues.

Summary

Involved in limb morphogenesis. Predicted to be extrinsic component of membrane. Predicted to be part of plasma membrane protein complex. [provided by Alliance of Genome Resources, Apr 2022]

IQCE Products(6)

mRNA	Protein	Name
NM_001287499.2	NP_001274428.1	IQ domain-containing protein E isoform 3
NM_001287500.2	NP_001274429.1	IQ domain-containing protein E isoform 4
NM_001287501.2	NP_001274430.1	IQ domain-containing protein E isoform 5
NM_001287502.2	NP_001274431.1	IQ domain-containing protein E isoform 6
NM_001410865.1	NP_001397794.1	IQ domain-containing protein E isoform 7
NM_152558.5	NP_689771.3	IQ domain-containing protein E isoform 1

IQCE Protein Structure

0
200
400
600
695 a.a.

Protein Preferred Names

Protein Names

IQ domain-containing protein E

Related Diseases

Diseases

Alias

Polydactyly, Postaxial, Type A7

PAPA7

Polydactyly, Postaxial, A7

Polydactyly, Postaxial, Type A1

Postaxial Polydactyly Type A	Polydactyly, Postaxial
Postaxial Polydactyly	PAPA1
Postaxial Polydactyly, Type A	Papa
Polydactyly, Postaxial, Types A1 And B	Postaxial Polydactyly Type B
Polydactyly Postaxial	Polydactyly, Postaxial A1
Polydactyly, Postaxial B	PAPB
Postaxial Polydactyly, Type A1/B	Polydactyly, Postaxial, Type A
Pyogenic Arthritis, Pyoderma Gangrenosum And Acne	Postaxial Polydactyly, Type B

Chromosome 2q35 Duplication Syndrome

Syndactyly	Syndactyly Type 1
Sdty1	Zygodactyly
Syndactyly, Type I	Sd1
Syndactyly, Type 1, With Or Without Craniosynostosis	Symphalangism
Non-Syndromic Syndactyly	Symphalangy
Webbing Of Digits	Syndactyly, Type 1

Retinal Degeneration

Degeneration Of Retina

Brachydactyly

Polydactyly

Non-Syndromic Polydactyly	Polydactyly, Postaxial
Postaxial Polydactyly	Supernumerary Digit
Extra Digits	Hyperdactyly
Polydactylia	Polydactylism
Supernumerary Digits

Weyers Acrofacial Dysostosis

Curry-Hall Syndrome	Weyers Acrodental Dysostosis
WAD	Acrodental Dysostosis Of Weyers
Acrofacial Dysostosis, Weyers Type	Acrofacial Dysostosis Of Weyers
Curry Hall Syndrome

Short-Rib Thoracic Dysplasia 14 With Polydactyly

SRTD14

Basal Cell Carcinoma, Infundibulocystic

Basal Cell Carcinoma With Follicular Differentiation	Infundibulocystic Basal Cell Carcinoma
Skin Infundibulocystic Basal Cell Carcinoma

Skin Tag

Fibroepithelial Polyp	Fibroepithelial Polyp Of Skin
Soft Fibroma	Skin Tags
Cutaneous Tag	Gardner Fibroma
Acrochordon	Fibroma Molle

Laurin-Sandrow Syndrome

Sandrow Syndrome	Tetramelic Mirror-Image Polydactyly
Mirror-Image Polydactyly	Mirror Hands And Feet With Nasal Defects
Tmip	LSS
Mip	Mirror Hands And Feets-Nasal Defects Syndrome
Fibula And Ulna, Duplication Of, With Absence Of Tibia And Radius	Miccor Hands And Feet With Nasal Defects
Mipduplication Of Fibuland Ulna With Absence Of Tibia And Radius	Fibula Ulna Duplication Tibia Radius Absence
Laurin Sandrow Syndrome	Duplication Of Fibula And Ulna With Absence Of Tibia And Radius
Segmental Laurin-Sandrow Syndrome	Laurin-Sandrow Syndrome, Segmental

Greig Cephalopolysyndactyly Syndrome

GCPS	Polysyndactyly With Peculiar Skull Shape
Polysyndactyly With Peculiars Skull Shape	Greig Syndrome
Cephalopolysyndactyly Syndrome	Greig Cephalo-Poly-Syndactyly Syndrome
Cephalopolysyndactyly, Greig Syndrome	Aarskog Syndrome

Acrofacial Dysostosis

Ellis-Van Creveld Syndrome

Chondroectodermal Dysplasia	Mesoectodermal Dysplasia
EVC	Ellis Van Creveld Syndrome
Mesodermic Dysplasia	Ellis-Van Creveld Dysplasia

Pallister-Hall Syndrome

PHS	Hypothalamic Hamartomas
Hypothalamic Hamartoblastoma, Hypopituitarism, Imperforate Anus, And Postaxial Polydactyly	Hypothalamic Hamartoblastoma Syndrome
Hamartoma Of The Hypothalamus	Pallister Hall Syndrome
Hall-Pallister Syndrome	Hypothalamic Hamartoblastoma Hypopituitarism Imperforate Anus And Postaxial Polydactyly
Hamartoma, Hypothalamic

Bardet-Biedl Syndrome

Bbs	Biedl-Bardet Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06878	IQCE Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	IQCE	MGD	MGI:1921489
Canis familiaris	IQCE	VGNC	VGNC:42076
Macaca mulatta	IQCE	VGNC	VGNC:73678
Rattus norvegicus	IQCE	RGD	RGD:1311349
Felis catus	IQCE	VGNC	VGNC:62962
Bos taurus	IQCE	VGNC	VGNC:30253