2. Gene
  3. NUDCD3 - NudC domain containing 3 Gene

NUDCD3 - NudC domain containing 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as NudCL

Gene ID: 23386 | Gene type: protein coding

About NUDCD3

Cytogenetic location: 7p13 Genomic coordinates (GRCh38): 7:44,379,119-44,490,658 (from NCBI)

This gene has 11 transcripts (splice variants), 196 orthologues and 2 paralogues. Ubiquitous expression in brain (RPKM 28.0), ovary (RPKM 14.4) and 25 other tissues.

Summary

The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition. [provided by RefSeq, Jul 2008]

NUDCD3 Products(1)

mRNA Protein Name
NM_015332.4 NP_056147.2 nudC domain-containing protein 3

NUDCD3 Protein Structure

Nudc_N

Nudc_N: N-terminal conserved domain of Nudc. (9 - 67)

CS

CS: CS domain (188 - 267)

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  • 361 a.a.
Protein Preferred Names Protein Names

nudC domain-containing protein 3

NudC-like protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09660 NUDCD3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NUDCD3 VGNC VGNC:75447
Bos taurus NUDCD3 VGNC VGNC:32324
Mus musculus NUDCD3 MGD MGI:2144158
Felis catus NUDCD3 VGNC VGNC:63911
Rattus norvegicus NUDCD3 RGD RGD:1642416