FRAT2 - FRAT regulator of WNT signaling pathway 2 Gene

Homo sapiens

Also known as FRAT-2

Gene ID: 23401 | Gene type: protein coding

About FRAT2

Cytogenetic location: 10q24.1 Genomic coordinates (GRCh38): 10:97,332,497-97,334,729 (from NCBI)

This gene has 1 transcript (splice variant), 61 orthologues and 1 paralogue.

Summary

The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the Wnt signaling pathway. It may be upregulated in tumor progression. [provided by RefSeq, Jul 2008]

FRAT2 Products(1)

mRNA	Protein	Name
NM_012083.3	NP_036215.1	GSK-3-binding protein FRAT2

FRAT2 Protein Structure

GSK-3_bind

0
100
200
233 a.a.

Protein Preferred Names

Protein Names

GSK-3-binding protein FRAT2

FRAT2, WNT signaling pathway regulator

Related Diseases

Diseases

Alias

Heinz Body Anemias

Heinz Body Anemia	Heinz Body Anemias, Alpha-
HEIBAN	Anemia, Heinz Body
Acquired Heinz Body Anemia

Nanophthalmos

Nanophthalmia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05091	FRAT2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	FRAT2	MGD	MGI:2673967
Bos taurus	FRAT2	VGNC	VGNC:55952
Macaca mulatta	FRAT2	VGNC	VGNC:72727
Rattus norvegicus	FRAT2	RGD	RGD:1591882

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