SLC16A8 - solute carrier family 16 member 8 Gene

Homo sapiens

Also known as MCT3; REMP

Gene ID: 23539 | Gene type: protein coding

About SLC16A8

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:38,078,137-38,084,184 (from NCBI)

This gene has 4 transcripts (splice variants), 170 orthologues and 13 paralogues. Broad expression in prostate (RPKM 2.1), testis (RPKM 0.9) and 20 other tissues.

Summary

SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across cell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied by OMIM, Apr 2010]

SLC16A8 Products(2)

mRNA	Protein	Name
NM_001394131.1	NP_001381060.1	monocarboxylate transporter 3 isoform 2
NM_013356.3	NP_037488.2	monocarboxylate transporter 3 isoform 1

SLC16A8 Protein Structure

MFS_1

0
100
200
300
400
504 a.a.

Protein Preferred Names

Protein Names

monocarboxylate transporter 3

MCT 3

Related Diseases

Diseases

Alias

Macular Degeneration, Age-Related, 1

Macular Degeneration	Age-Related Macular Degeneration
Macular Degeneration, Age-Related	Age Related Macular Degeneration
Age Related Macular Degeneration 1	ARMD1
Senile Macular Degeneration	Maculopathy, Age-Related, 1
Macular Degeneration, Age-Related, Reduced Risk Of	Age Related Maculopathy 1
Age Related Maculopathies	Age Related Maculopathy
Senile Macular Retinal Degeneration	Macular Degeneration Of Retina
Age-Related Maculopathy	Amd
Armd	Age-Related Maculopathy, Susceptibility To
Maculopathy Age-Related	Macular Degeneration, Age-Related, 1, Susceptibility To
Maculopathy, Age-Related	Macular Degeneration, Age-Related, Type 1
Macular Degeneration, Age-Related, 2

Fundus Dystrophy

Retinal Dystrophy	Retinal Dystrophies
Dystrophy, Retinal

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13032	SLC16A8 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SLC16A8	VGNC	VGNC:65215
Macaca mulatta	SLC16A8	VGNC	VGNC:108037
Canis familiaris	SLC16A8	VGNC	VGNC:46246
Rattus norvegicus	SLC16A8	RGD	RGD:69282
Mus musculus	SLC16A8	MGD	MGI:1929519
Bos taurus	SLC16A8	VGNC	VGNC:34694

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