EML2 - EMAP like 2 Gene

Homo sapiens

Also known as ELP70; EMAP2; EMAP-2

Gene ID: 24139 | Gene type: protein coding

About EML2

Cytogenetic location: 19q13.32 Genomic coordinates (GRCh38): 19:45,609,400-45,645,629 (from NCBI)

This gene has 31 transcripts (splice variants), 187 orthologues and 9 paralogues. Ubiquitous expression in esophagus (RPKM 8.7), skin (RPKM 8.5) and 25 other tissues.

Summary

Enables microtubule binding activity. Involved in negative regulation of microtubule polymerization and regulation of microtubule nucleation. Colocalizes with mitotic spindle. [provided by Alliance of Genome Resources, Apr 2022]

EML2 Products(7)

mRNA	Protein	Name
NM_001193268.3	NP_001180197.1	echinoderm microtubule-associated protein-like 2 isoform 1
NM_001193269.2	NP_001180198.1	echinoderm microtubule-associated protein-like 2 isoform 3
NM_001352051.2	NP_001338980.1	echinoderm microtubule-associated protein-like 2 isoform 4
NM_001352052.1	NP_001338981.1	echinoderm microtubule-associated protein-like 2 isoform 5
NM_001352053.2	NP_001338982.1	echinoderm microtubule-associated protein-like 2 isoform 6
NM_001352054.2	NP_001338983.1	echinoderm microtubule-associated protein-like 2 isoform 7
NM_012155.4	NP_036287.1	echinoderm microtubule-associated protein-like 2 isoform 2

EML2 Protein Structure

HELP

WD40

0
100
200
300
400
500
600
649 a.a.

Protein Preferred Names

Protein Names

echinoderm microtubule-associated protein-like 2

echinoderm MT-associated protein (EMAP)-like protein 70

Related Diseases

Diseases

Alias

Sulfonamide Allergy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04354	EML2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	EML2	VGNC	VGNC:28476
Felis catus	EML2	VGNC	VGNC:61849
Mus musculus	EML2	MGD	MGI:1919455
Rattus norvegicus	EML2	RGD	RGD:621066
Canis familiaris	EML2	VGNC	VGNC:40347
Others	EML2	NCBI