2. Gene
  3. Ada - adenosine deaminase Gene

Ada - adenosine deaminase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 24165 | Gene type: protein coding

About Ada

Primary_assembly 3: 152,398,747-152,447,088 reverse strand.mRatBN7.2:CM026976.1

This gene has 4 transcripts (splice variants), 218 orthologues, 1 paralogue and is associated with 51 phenotypes. Biased expression in Lung (RPKM 737.7), Thymus (RPKM 689.8) and 7 other tissues.

Summary

Enables Adenosine Deaminase activity and purine nucleoside binding activity. Involved in several processes, including adenosine metabolic process; negative regulation of circadian sleep/wake cycle, non-REM sleep; and response to vitamin E. Located in dendrite cytoplasm; extracellular space; and neuronal cell body. Used to study hypertension; peritonitis; and pulmonary edema. Biomarker of hyperglycemia; leptospirosis; lung disease; and trypanosomiasis. Human ortholog(s) of this gene implicated in Adenosine Deaminase deficiency; asthma; and severe combined immunodeficiency. Orthologous to human ADA (Adenosine Deaminase). [provided by Alliance of Genome Resources, Apr 2022]

Ada Products(1)

mRNA Protein Name
NM_130399.2 NP_569083.1 adenosine deaminase

Ada Protein Structure

A_deaminase

A_deaminase: pfam00962 (9 - 348)

  • 0
  • 100
  • 200
  • 300
  • 352 a.a.
Protein Preferred Names Protein Names

adenosine deaminase

adenosine aminohydrolase

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-17377 Vicriviroc maleate 99.91% Phase 3
Pre-clinical Phase
Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-103160A EHNA hydrochloride Inhibitor 99.61% Unkown
HY-W011552 2'-O-Methyladenosine 99.44% Unkown
HY-116578 Metopimazine 98.03% Unkown
HY-N7368 Hibifolin Inhibitor 99.70% Unkown
HY-103159 1-Deazaadenosine Inhibitor ≥98.0% Unkown
HY-103237 L-Adenosine Inhibitor ≥97.0% Unkown
HY-D0855 ADA ≥97.0% Unkown
HY-117260 Coformycin Inhibitor / Unkown
HY-158009 SGF29-IN-1 Inhibitor / Unkown
HY-P5201S VTSEGAGLQLQK-13C6,15N2 / Unkown
HY-RS00258 ADA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00259 Ada Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00260 Ada Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00261 ADA2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-N12840 Logmalicid B / Unkown
HY-W753672 2'-O-Methyladenosine-d3 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ada NCBI NCBI:100
Macaca fascicularis Ada NCBI NCBI:102137458
Mus musculus Ada NCBI NCBI:11486
Macaca mulatta Ada NCBI NCBI:717897