1. Gene
  2. SPDYA - speedy/RINGO cell cycle regulator family member A Gene

SPDYA - speedy/RINGO cell cycle regulator family member A Gene

Homo sapiens

Also known as SPY1; SPDY1; RINGO3; RINGOA

Gene ID: 245711 | Gene type: protein coding

About SPDYA

Cytogenetic location: 2p23.2 Genomic coordinates (GRCh38): 2:28,810,834-28,850,610 (from NCBI)

This gene has 7 transcripts (splice variants), 188 orthologues and 1 paralogue. Biased expression in testis (RPKM 22.5), duodenum (RPKM 1.7) and 10 other tissues.

Summary

Enables protein kinase activator activity and protein kinase binding activity. Involved in several processes, including G1/S transition of mitotic cell cycle; positive regulation of cell population proliferation; and positive regulation of protein kinase activity. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SPDYA Products(3)

mRNA Protein Name
NM_001008779.1 NP_001008779.1 speedy protein A isoform 2
NM_001142634.2 NP_001136106.1 speedy protein A isoform 1
NM_182756.4 NP_877433.2 speedy protein A isoform 1

SPDYA Protein Structure

Spy1

Spy1: Cell cycle regulatory protein (69 - 199)

  • 0
  • 100
  • 200
  • 313 a.a.
Protein Preferred Names Protein Names

speedy protein A

RINGO A

Related Diseases

Diseases Alias
Hypertrophy Of Breast

Breasts Enlarged

Large Breast

Hypertrophy Of Breast Nos

Hypertrophy Of Male Breast

Hypertrophic Breast

Excessive Development Of Breast

Macromastia

Mastoplastia

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris SPDYA VGNC VGNC:46728
Mus musculus SPDYA MGD MGI:1918141
Bos taurus SPDYA VGNC VGNC:54492
Macaca mulatta SPDYA VGNC VGNC:106224
Felis catus SPDYA VGNC VGNC:65629
Rattus norvegicus SPDYA RGD RGD:621730