Tacr1 - tachykinin receptor 1 Gene

Rattus norvegicus

Also known as Tac1r

Gene ID: 24807 | Gene type: protein coding

About Tacr1

Primary_assembly 4: 114,920,844-115,089,733 forward strand.mRatBN7.2:CM026977.1

This gene has 1 transcript (splice variant), 270 orthologues, 50 paralogues and is associated with 34 phenotypes. Biased expression in Spleen (RPKM 7.7), Brain (RPKM 7.5) and 8 other tissues.

Summary

Enables substance P receptor activity. Involved in several processes, including learning or memory; positive regulation of secretion; and regulation of cell migration. Located in several cellular components, including cell body; cell surface; and dendrite. Used to study central sleep apnea; cystitis; pancreatitis; and pulmonary hypertension. Biomarker of acute necrotizing pancreatitis; allergic rhinitis; asthma; colitis; and respiratory syncytial virus infectious disease. Human ortholog(s) of this gene implicated in exercise-induced bronchoconstriction. Orthologous to human TACR1 (tachykinin receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Tacr1 Products(1)

mRNA	Protein	Name
NM_012667.3	NP_036799.1	substance-P receptor

Tacr1 Protein Structure

7tm_GPCRs

0
100
200
300
407 a.a.

Protein Preferred Names

Protein Names

substance-P receptor

NK-1 receptor	NK-1R
SPR	neurokinin 1 receptor
substance p receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14143	TACR1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS14144	Tacr1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS14145	Tacr1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tacr1	NCBI	NCBI:6869

Name
Email *

	Sorry, but the email address you supplied was invalid.