2. Gene
  3. TNF - tumor necrosis factor Gene

TNF - tumor necrosis factor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Tnfa; RATTNF; TNF-alpha

Gene ID: 24835 | Gene type: protein coding

About TNF

Primary_assembly 20: 3,622,011-3,624,629 forward strand.mRatBN7.2:CM026993.1

This gene has 2 transcripts (splice variants), 246 orthologues, 8 paralogues and is associated with 417 phenotypes. Biased expression in Thymus (RPKM 3.7), Spleen (RPKM 26.5) and 9 other tissues.

Summary

Enables tumor necrosis factor receptor binding activity. Involved in several processes, including positive regulation of cell communication; positive regulation of macromolecule metabolic process; and positive regulation of neuron death. Located in several cellular components, including external side of plasma membrane; extracellular space; and neuronal cell body. Used to study several diseases, including cerebrovascular disease (multiple); liver disease (multiple); peptic esophagitis; perinatal necrotizing enterocolitis; and periventricular leukomalacia. Biomarker of several diseases, including brain disease (multiple); congestive heart failure (multiple); inflammatory bowel disease (multiple); lung disease (multiple); and non-alcoholic fatty liver disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); lung disease (multiple); and skin disease (multiple). Orthologous to human TNF (tumor necrosis factor). [provided by Alliance of Genome Resources, Apr 2022]

TNF Products(1)

mRNA Protein Name
NM_012675.3 NP_036807.1 tumor necrosis factor

TNF Protein Structure

TNF

TNF: pfam00229 (104 - 234)

  • 0
  • 100
  • 200
  • 235 a.a.
Protein Preferred Names Protein Names

tumor necrosis factor

cachectin

tumor necrosis factor (TNF superfamily, member 2)

tumor necrosis factor ligand superfamily member 2

Recombinant TNF Proteins

Cat. No. Product Name Accession Purity
HY-P7108 TNF-alpha/TNFSF2 Protein, Rat (P.pastoris) P16599 (L80-L235) ≥95%
HY-P70697 TNF-alpha/TNFSF2 Protein, Rat P16599 (L80-L235) ≥95%

Related Agents

Approval
Bioactive Molecules (15)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12085 Apremilast 99.91% Yes
HY-103399 Trovafloxacin mesylate Inhibitor 99.56% Unkown
HY-N0281 Daphnetin 99.86% Unkown
HY-13682 Mifamurtide ≥99.0% Unkown
HY-B1077 Penfluridol 99.93% Unkown
HY-B1201 Tiratricol Inhibitor 99.60% Yes
HY-A0170 Trovafloxacin Inhibitor 98.99% Unkown
HY-B0446 Naphazoline hydrochloride 98.37% Unkown
HY-13682B Mifamurtide sodium ≥98.0% Unkown
HY-B0164 Mizolastine Antagonist 99.94% Unkown
HY-B0513 Methylthiouracil Inhibitor ≥98.0% Unkown
HY-111326A Naphazoline nitrate ≥98.0% Unkown
HY-13682C Mifamurtide TFA ≥98.0% Unkown
HY-111326 Naphazoline / Unkown
HY-B0164A Mizolastine dihydrochloride Antagonist / Unkown
Inhibitory Antibodies (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9970 Infliximab Inhibitor 90.30% Unkown
HY-P9908 Adalimumab Inhibitor 99.62% Unkown
HY-108847 Etanercept Inhibitor 99.20% Unkown
HY-P9953 Certolizumab pegol Inhibitor 99.30% Unkown
HY-P99111 Golimumab 99.68% Unkown
HY-P99796 Ozoralizumab Inhibitor 99.80% Unkown
Clinical Phase
Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Phase
HY-N8277 Kdo2-Lipid A ammonium ≥95.0% Phase 4
HY-11109 Resatorvid Inhibitor 99.95% Phase 3
HY-13743 Roquinimex Inhibitor 98.93% Phase 3
HY-13740 Resiquimod 99.95% Phase 2
HY-16591 Birinapant 99.70% Phase 2
HY-15509A Semapimod tetrahydrochloride Inhibitor 98.43% Phase 2
HY-119307 Apratastat Inhibitor 99.67% Phase 2
HY-145726 ISIS 104838 Inhibitor 93.70% Phase 2
HY-100376 CPI-1189 Inhibitor 98.49% Phase 2
HY-18862 PF-03715455 Inhibitor / Phase 2
HY-13518 Piceatannol 98.90% Phase 1
HY-107390A AX-024 hydrochloride Inhibitor 99.75% Phase 1
HY-15507 VGX-1027 Inhibitor 99.76% Phase 1
HY-19717 DCVC Inhibitor 99.83% Phase 1
HY-N0803 Myrcene Inhibitor ≥75.0% Phase 1
HY-N8691 2',6'-Dihydroxy-4'-methoxydihydrochalcone Inhibitor / Phase 1
Inhibitory Antibodies (14)
Cat. No. Product Name Effect
Purity Phase
HY-P99252 Itolizumab 95.00% Phase 3
HY-P990070 Zigakibart Inhibitor / Phase 3
HY-P99499 Cetrelimab 100.00% Phase 3
HY-P99578 Tanfanercept Inhibitor / Phase 3
HY-P99772 Onfekafusp alfa / Phase 3
HY-P99670 Iscalimab Inhibitor 99.15% Phase 2
HY-P99315 Ruplizumab Inhibitor 99.84% Phase 2
HY-P99810 Quisovalimab 96.18% Phase 2
HY-P99704 Licaminlimab Inhibitor 96.10% Phase 2
HY-P99775 Placulumab Inhibitor / Phase 2
HY-P99940 Remtolumab Inhibitor 99.24% Phase 2
HY-P99945 Revdofilimab Activator 99.35% Phase 1
HY-P99361 Enavatuzumab Inhibitor ≥95.0% Phase 1
HY-P99178 CTX-471 99.42% Phase 1
Pre-clinical Phase
Bioactive Molecules (352)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13453 BAY 11-7082 99.98% Unkown
HY-N0822 Shikonin Inhibitor 99.80% Unkown
HY-15648B GSK-J4 99.64% Unkown
HY-P0224 N-Formyl-Met-Leu-Phe Inhibitor 99.83% Unkown
HY-103490 Takinib 99.31% Unkown
HY-12326A c-di-AMP disodium Agonist 99.88% Unkown
HY-108473 CU-CPT 4a Inhibitor 98.91% Unkown
HY-110203 R-7050 Antagonist 98.55% Unkown
HY-13812 QNZ Inhibitor 99.51% Unkown
HY-10172 IMD-0354 Inhibitor 99.51% Unkown
HY-109804 CORM-401 Inhibitor 98.27% Unkown
HY-138682 STING-IN-2 Inhibitor 98.58% Unkown
HY-122882 HOIPIN-8 99.89% Unkown
HY-123942 Diprovocim Agonist 98.35% Unkown
HY-133122 UCB-9260 Inhibitor 99.96% Unkown
HY-13229 BOC-D-FMK Inhibitor ≥95.0% Unkown
HY-N0633 Muscone Inhibitor ≥98.0% Unkown
HY-110133 JTE-607 Inhibitor 99.27% Unkown
HY-100339 GSK583 Inhibitor 98.74% Unkown
HY-15648F GSK-J4 hydrochloride Inhibitor 98.83% Unkown
HY-N0029 Forsythoside B 99.99% Unkown
HY-125402 GSK-843 99.18% Unkown
HY-100211 TAPI-2 Inhibitor 99.46% Unkown
HY-110353 CU-T12-9 Agonist 98.94% Unkown
HY-N0297 Sinensetin Inhibitor 99.87% Unkown
HY-N0509 Astilbin 99.97% Unkown
HY-19744 T6167923 Inhibitor 99.08% Unkown
HY-107427 PF-3644022 Inhibitor 99.65% Unkown
HY-147141 HS-276 Inhibitor 98.59% Unkown
HY-N0472 Geraniin Inhibitor 99.84% Unkown
HY-15511 Tyrphostin A9 Inhibitor 99.87% Unkown
HY-N0194 Asiatic acid 99.40% Unkown
HY-32018 Cot inhibitor-2 Inhibitor 99.22% Unkown
HY-131249 MK2-IN-3 Inhibitor 99.58% Unkown
HY-P1860 TNF-α (31-45), human 99.77% Unkown
HY-N0043 Ginsenoside Rd Inhibitor 99.88% Unkown
HY-134471 TNF-α-IN-2 Inhibitor 98.12% Unkown
HY-N0619 Mulberroside A Inhibitor 99.86% Unkown
HY-14622 Necrostatin 2 Inhibitor 99.92% Unkown
HY-111255 SPD304 Inhibitor 99.35% Unkown
HY-156798 ADS032 99.74% Unkown
HY-147045 UCB-5307 Inhibitor 97.37% Unkown
HY-N0405 Orientin Inhibitor 99.02% Unkown
HY-N0316 Mollugin 99.48% Unkown
HY-19975 RN-1734 Antagonist 99.86% Unkown
HY-101448 TMI-1 99.59% Unkown
HY-126360 Oxazolone ≥98.0% Unkown
HY-N6607 Tryptanthrin 99.89% Unkown
HY-142618 TNF-α-IN-6 Inhibitor 99.58% Unkown
HY-133807 Benpyrine Inhibitor 99.74% Unkown
HY-101849 Fasentin ≥98.0% Unkown
HY-148141 JPE-1375 Antagonist 99.94% Unkown
HY-150725 ODN 1585 Inducer 93.90% Unkown
HY-N1949 Homoplantaginin Inhibitor 99.90% Unkown
HY-N0936 Coixol Inhibitor 99.58% Unkown
HY-103360 J-113863 Antagonist ≥99.0% Unkown
HY-107390 AX-024 Inhibitor 99.29% Yes
HY-N7637 Tubuloside B Inhibitor 99.95% Unkown
HY-N0722 Neochlorogenic acid Inhibitor 99.07% Unkown
HY-123984 LTβR-IN-1 Activator 99.79% Unkown
HY-N0604 Ginsenoside Rh1 Inhibitor ≥98.0% Unkown
HY-104073 CAY10602 Activator 98.65% Unkown
HY-P1832A PTD-p65-P1 Peptide TFA 99.14% Unkown
HY-W010201 Citronellol Activator ≥98.0% Unkown
HY-N0042 Ginsenoside Rc ≥98.0% Unkown
HY-103435 Vialinin A Inhibitor ≥99.0% Unkown
HY-110177 SP-100030 Inhibitor 99.86% Unkown
HY-N0569 Madecassic acid Inhibitor 99.23% Unkown
HY-N2350 Cynaropicrin Inhibitor 99.79% Unkown
HY-111255A SPD304 dihydrochloride Inhibitor 99.96% Unkown
HY-124750 NecroX-7 Inhibitor 99.69% Unkown
HY-125527 Resolvin D1 99.60% Unkown
HY-134911 HS-243 Inhibitor 99.88% Unkown
HY-100735 C 87 Inhibitor 98.03% Unkown
HY-130252 YQ128 Inhibitor 99.83% Unkown
HY-12511 SKF-86002 Inhibitor 99.66% Unkown
HY-N7056 4'-Hydroxychalcone Inhibitor 99.66% Unkown
HY-108642B AMG-548 dihydrochloride Inhibitor 99.91% Unkown
HY-118922 IW927 Antagonist 99.04% Unkown
HY-N0041 Ginsenoside Rb3 Inhibitor 99.12% Unkown
HY-128348 PK68 Inhibitor 99.92% Unkown
HY-N0613 Sauchinone Inhibitor 99.89% Unkown
HY-128598 MD2-TLR4-IN-1 Inhibitor 99.62% Unkown
HY-132248 C5 Lenalidomide Inhibitor / Unkown
HY-128686 KAG-308 Agonist 99.88% Unkown
HY-113402A Gamma-glutamylcysteine TFA 95.20% Unkown
HY-120823 PF-05381941 Inhibitor 99.75% Unkown
HY-156454 UCB-6876 Inhibitor 99.96% Unkown
HY-B0392 (S)-(+)-Rolipram 99.77% Unkown
HY-113953 Z-Asp-CH2-DCB Inhibitor 99.28% Unkown
HY-114360A Taurohyodeoxycholic acid sodium Inhibitor ≥98.0% Unkown
HY-N1356 Reticuline Inhibitor 98.91% Unkown
HY-P1847A IKKγ NBD Inhibitory Peptide TFA 99.31% Unkown
HY-102040 Hispidol Inhibitor 98.70% Unkown
HY-12326B c-di-AMP diammonium Agonist 99.36% Unkown
HY-N2110 Phellopterin 99.94% Unkown
HY-32015 Cot inhibitor-1 Inhibitor 98.06% Unkown
HY-135674 SR-318 Inhibitor 99.89% Unkown
HY-112275 TNF-α-IN-1 Inhibitor 99.42% Unkown
HY-116626 SM-7368 Inhibitor 99.90% Unkown
HY-118694 TAPI-0 Inhibitor 98.01% Unkown
HY-N0617 Sanggenon C 98.50% Unkown
HY-N9965 2'-Fucosyllactose Inhibitor 99.95% Unkown
HY-12326 c-di-AMP Agonist 99.29% Unkown
HY-133807A (Rac)-Benpyrine Inhibitor 99.30% Unkown
HY-147263 Dovramilast Inhibitor 99.83% Unkown
HY-124151 Adenosine-2'-monophosphate Activator ≥98.0% Unkown
HY-131945 CU-115 Antagonist 99.55% Unkown
HY-N0907 Ginsenoside Rg6 99.13% Unkown
HY-N1940 β-Anhydroicaritin Inhibitor 99.09% Unkown
HY-N2252 Licarin A Inhibitor 98.48% Unkown
HY-N3063 Pimaric acid 99.83% Unkown
HY-N6253 Pinoresinol Inducer 99.69% Unkown
HY-N6857 Armepavine Inhibitor 99.53% Unkown
HY-19667A BMS-561392 formate Inhibitor / Unkown
HY-W082785A L6H21 99.46% Unkown
HY-129113 α-​Chaconine Inhibitor 99.04% Unkown
HY-152956 STING agonist-23 Agonist 99.16% Unkown
HY-N0358 1,4-Dicaffeoylquinic acid Inhibitor 99.80% Unkown
HY-N1987 Cucurbitacin IIb Inducer ≥99.0% Unkown
HY-N3316 Martynoside Antagonist ≥99.0% Unkown
HY-N6246 Asperulosidic Acid Inhibitor 99.72% Unkown
HY-145498 HDMAPP triammonium Activator ≥90.0% Unkown
HY-150729 ODN 1982 98.78% Unkown
HY-N0506 Rosarin 99.94% Unkown
HY-N0906 Ginsenoside Rk3 Inhibitor 98.85% Unkown
HY-N2855 Alphitolic acid ≥97.0% Unkown
HY-N9445 Lacto-N-neotetraose 99.71% Unkown
HY-P3722A Mca-PLAQAV-Dpa-RSSSR-NH2 TFA 99.21% Unkown
HY-12557 γ-Glutamylvaline 99.73% Unkown
HY-13740S Resiquimod-d5 99.84% Unkown
HY-131707 LEO 39652 Inhibitor 99.51% Unkown
HY-110077 API-1 / Unkown
HY-110246 Quin C1 98.47% Unkown
HY-112389 p38 MAP Kinase Inhibitor III Inhibitor ≥98.0% Unkown
HY-117082 UTL-5g Inhibitor 98.97% Unkown
HY-148454 Necroptosis-IN-3 Inhibitor 99.77% Unkown
HY-151966 TD1092 99.49% Unkown
HY-N0857 Deoxyandrographolide Activator 99.87% Unkown
HY-N4323 14-Deoxyandrographolide Inhibitor 99.47% Unkown
HY-N6073 Soyasapogenol A Inhibitor 99.06% Unkown
HY-N9315 Episappanol Inhibitor 98.57% Unkown
HY-P1860A TNF-α (31-45), human TFA / Unkown
HY-P2320 IDR-1 Inhibitor 99.44% Unkown
HY-W013557 3-Hydroxyxanthone Inhibitor ≥98.0% Unkown
HY-101041 (E)-AG 556 Inhibitor 99.92% Unkown
HY-106359A Delmitide acetate Inhibitor 98.55% Yes
HY-112456 IKK2-IN-4 Inhibitor 99.36% Unkown
HY-12085S Apremilast-d5 98.63% Unkown
HY-122786 3-O-Methylviridicatin Inhibitor / Unkown
HY-123194 SIRT2/6-IN-1 Inhibitor 95.69% Unkown
HY-126114 Lupeol acetate Inhibitor ≥98.0% Unkown
HY-129151 Ganoderic acid C1 ≥95.0% Unkown
HY-133807B (R)-Benpyrine 99.17% Unkown
HY-135808 BIZ 114 Inhibitor ≥98.0% Unkown
HY-147696 SMTIN-T140 99.58% Unkown
HY-151876 Glucocorticoid receptor modulator 1 99.79% Unkown
HY-152959 STING agonist-26 Agonist 99.56% Unkown
HY-160178 Glucocorticoid receptor agonist-3 Ala-Ala-Mal 99.72% Unkown
HY-160179 Glucocorticoid receptor agonist-4 Agonist 99.80% Unkown
HY-18754A FR 167653 Inhibitor 99.87% Unkown
HY-N0811 Anemarsaponin B Inhibitor / Unkown
HY-N3595 Cleomiscosin A Inhibitor 99.15% Unkown
HY-N3807 Enniatin B1 Inhibitor ≥97.0% Unkown
HY-N6927 Isoforskolin Inhibitor ≥98.0% Unkown
HY-P1875A TNF-α (46-65), human TFA 99.20% Unkown
HY-P3149B LEESGGGLVQPGGSMK acetate 99.01% Unkown
HY-P3203A DSTYSLSSTLTLSK TFA 98.11% Unkown
HY-118157 3,5,7-Trimethoxyflavone 98.94% Unkown
HY-156060 NCI126224 Inhibitor 99.88% Unkown
HY-P2612A WP9QY TFA Antagonist / Unkown
HY-131340 LASSBio-1632 Inhibitor / Unkown
HY-132195 RORγt inverse agonist 14 Inhibitor / Unkown
HY-19667 BMS-561392 Inhibitor / Unkown
HY-150612 (R)-STU104 Inhibitor / Unkown
HY-100211A (R)-TAPI-2 / Unkown
HY-106359 Delmitide Inhibitor / Unkown
HY-108162A Ataquimast Inhibitor / Unkown
HY-108623 Atizoram Inhibitor / Unkown
HY-108641 SKF-86002 dihydrochloride Inhibitor / Unkown
HY-108642A AMG-548 hydrochloride Inhibitor / Unkown
HY-108953 (S)-Quinolactacine A Inhibitor / Unkown
HY-111317 SIRT1 activator 3 Activator / Unkown
HY-114221 Org 48762-0 Inhibitor / Unkown
HY-114981 SRTCX1002 Activator / Unkown
HY-115351 GW-3333 Inhibitor / Unkown
HY-115913 PDE4-IN-6 Inhibitor / Unkown
HY-115976 COX-2-IN-10 Inhibitor / Unkown
HY-118101 15-Deoxy-Δ12,14-prostaglandin A1 / Unkown
HY-120041 ND-2158 Inhibitor / Unkown
HY-121401 Myrtenal / Unkown
HY-121996 Prostaglandin E2 Ethanolamide / Unkown
HY-122292 Celastramycin A Inhibitor / Unkown
HY-122521 Sootepin D Inhibitor / Unkown
HY-123542 ONO-3403 / Unkown
HY-124003 Phytomonic acid / Unkown
HY-125527S Resolvin D1-d5 / Unkown
HY-126414 Methylenedihydrotanshinquinone / Unkown
HY-128423AS Tylvalosin-d9 / Unkown
HY-134950 (E)-C-HDMAPP ammonium Activator / Unkown
HY-136010 RIP2 Kinase Inhibitor 4 Inhibitor / Unkown
HY-141582 Ceramide 3 / Unkown
HY-142069 KB-R7785 Inhibitor / Unkown
HY-142958 NF-κB-IN-2 / Unkown
HY-14305 BMS-582949 / Unkown
HY-143410 Anti-inflammatory agent 16 Inhibitor / Unkown
HY-144368 CO delivery molecule 1 / Unkown
HY-144727 Anti-inflammatory agent 11 Inhibitor / Unkown
HY-144737 Anti-inflammatory agent 15 Inhibitor / Unkown
HY-145492 Δ7(Z)-C14-HSL / Unkown
HY-145726A ISIS 104838 sodium 93.70% Unkown
HY-146419 Anti-inflammatory agent 20 Inhibitor / Unkown
HY-146435 Anti-inflammatory agent 22 Inhibitor / Unkown
HY-146483 Anti-Aβ agent 1A Inhibitor / Unkown
HY-146547 Anti-inflammatory agent 17 Inhibitor / Unkown
HY-146723 IKKβ-IN-1 Inhibitor / Unkown
HY-146765 AMS-17 Inhibitor / Unkown
HY-147078 EJMC-1 Inhibitor 99.69% Unkown
HY-147086 CAY10789 99.84% Unkown
HY-147506 NOD2 antagonist 1 Antagonist / Unkown
HY-147697 LSD1-IN-21 Inhibitor / Unkown
HY-147712 PKC-IN-4 Inhibitor / Unkown
HY-147924 Keap1-Nrf2-IN-11 Inhibitor / Unkown
HY-147950 PDE4-IN-10 Inhibitor / Unkown
HY-148606 STING modulator-3 Inhibitor / Unkown
HY-148908 TNF-α-IN-8 / Unkown
HY-149331 TNF-α-IN-11 Inhibitor / Unkown
HY-149485 JNK2-IN-1 Inhibitor / Unkown
HY-149816 Anti-inflammatory agent 41 Inhibitor / Unkown
HY-149984 MAO-B-IN-21 Inhibitor / Unkown
HY-150219 ODN M326 Agonist / Unkown
HY-150725A Biotin-labeled ODN 1585 sodium / Unkown
HY-150725B FITC-labeled ODN 1585 sodium / Unkown
HY-150729A ODN 1982 sodium 98.78% Unkown
HY-151188 DHU-Se1 Inhibitor / Unkown
HY-151369 AV123 Inhibitor / Unkown
HY-152213 BET-IN-13 Inhibitor / Unkown
HY-152957 STING agonist-24 Agonist / Unkown
HY-152958 STING agonist-25 Agonist / Unkown
HY-152961 STING agonist-28 Agonist / Unkown
HY-153329 TNF-α-IN-9 Inhibitor / Unkown
HY-153330 TNF-α-IN-10 Inhibitor / Unkown
HY-153579 Anti-inflammatory agent 42 Inhibitor ≥98.0% Unkown
HY-153952 Immuno modulator-1 Inhibitor / Unkown
HY-154698 Homouridine / Unkown
HY-155027 DPP-4-IN-8 Inhibitor / Unkown
HY-15509 Semapimod Inhibitor / Unkown
HY-155179 ZMF-23 Inhibitor / Unkown
HY-155199 PDE1-IN-5 Inhibitor / Unkown
HY-155243 12R-LOX-IN-1 Inhibitor / Unkown
HY-155405 Anti-inflammatory agent 64 Inhibitor / Unkown
HY-155753 Anti-inflammatory agent 50 Inhibitor / Unkown
HY-155759 HMGB1-IN-2 Inhibitor / Unkown
HY-155820 Anti-inflammatory agent 54 Inhibitor / Unkown
HY-155821 Anti-inflammatory agent 55 Inhibitor / Unkown
HY-155998 NF-κB-IN-11 Inhibitor / Unkown
HY-156025 HCAR2 agonist 1 / Unkown
HY-156297 β5i-IN-1 Inhibitor / Unkown
HY-156367 RIPK1-IN-16 Inhibitor / Unkown
HY-157456 RIPK1-IN-19 Inhibitor / Unkown
HY-157546 VEGFR-2-IN-40 Inhibitor / Unkown
HY-157809 Anti-inflammatory agent 74 Inhibitor / Unkown
HY-157992 LM-021 Inhibitor / Unkown
HY-160027 TNF-alpha-IN-1 Inhibitor / Unkown
HY-160180 Glucocorticoid receptor agonist-4 Ala-Ala-Mal / Unkown
HY-160231 ssRNA42 sodium Activator / Unkown
HY-160433 TNF-α-IN-12 Inhibitor / Unkown
HY-160434 TNF-α-IN-13 Inhibitor / Unkown
HY-160435 TNF-α-IN-14 Inhibitor / Unkown
HY-160436 TNF-α-IN-15 Inhibitor / Unkown
HY-160437 TNF-α-IN-16 Inhibitor / Unkown
HY-161016 TNF/IFN-γ-IN-1 Inhibitor / Unkown
HY-161240 MAO-B-IN-30 Inhibitor 98.53% Unkown
HY-161381 PDE4-IN-15 Inhibitor / Unkown
HY-161520 Glucocorticoid receptor/NF-κB modulator-1 / Unkown
HY-161620 DW18134 Inhibitor / Unkown
HY-162097 RIPK1-IN-20 Inhibitor / Unkown
HY-162116 TLR7 agonist 18 Agonist / Unkown
HY-162316 NF-κB-IN-15 Inhibitor / Unkown
HY-163280 JGB-1-155 Activator / Unkown
HY-163368 HDAC6-IN-34 Inhibitor / Unkown
HY-18754 FR 167653 free base Inhibitor / Unkown
HY-18759 BMS-751324 Inhibitor / Unkown
HY-19717S DCVC-13C3,15N / Unkown
HY-N0041R Ginsenoside Rb3 (Standard) Inhibitor / Unkown
HY-N0043R Ginsenoside Rd (Standard) Inhibitor / Unkown
HY-N0569R Madecassic acid (Standard) Inhibitor / Unkown
HY-N0604R Ginsenoside Rh1 (Standard) Inhibitor / Unkown
HY-N0619A cis-Mulberroside A Inhibitor / Unkown
HY-N0976 1,11b-Dihydro-11b-hydroxymedicarpin / Unkown
HY-N10009 Cudraflavone B / Unkown
HY-N10047 7,8-Didehydrocimigenol Inhibitor / Unkown
HY-N10448 Sinulatumolin E Inhibitor / Unkown
HY-N10453 Sinulatumolin D / Unkown
HY-N10454 Sinulatumolin C Inhibitor / Unkown
HY-N10835 Gnetumontanin B / Unkown
HY-N1125 Triptobenzene H / Unkown
HY-N11768 4-Methoxylonchocarpin Inhibitor / Unkown
HY-N11892 7-O-Methylaloesinol Inhibitor / Unkown
HY-N11996 Aloenin aglycone / Unkown
HY-N12042 Taxamairin B Inhibitor / Unkown
HY-N12186 Sibiricine / Unkown
HY-N12653 Exserohilone Inhibitor / Unkown
HY-N12743 Farobin A Inhibitor / Unkown
HY-N1326 Santamarine / Unkown
HY-N3364 Lucidone Inhibitor / Unkown
HY-N3380 Linderaspirone A Inhibitor / Unkown
HY-N3421 Koaburaside Inhibitor / Unkown
HY-N3552 Catalposide Inhibitor ≥98.0% Unkown
HY-N3625 Coronalolic acid Inhibitor / Unkown
HY-N4061 Hedycoronen A Inhibitor / Unkown
HY-N4275 Oleaside A / Unkown
HY-N4285 Negletein Inhibitor ≥99.0% Unkown
HY-N7699A D-Trimannuronic acid Activator / Unkown
HY-N8371 Shizukaol B Inhibitor / Unkown
HY-N8413 Chlojaponilactone B Inhibitor / Unkown
HY-N8593 Undecane Inhibitor / Unkown
HY-N8593S Undecane-d24 / Unkown
HY-N8816 Stipuleanoside R2 / Unkown
HY-N8936 Narchinol B / Unkown
HY-N9000 Loganic acid 6′-O-β-D-glucoside / Unkown
HY-N9587 Tricin 7-O-β-D-glucopyranoside Inducer / Unkown
HY-N9699 8α-Hydroxyhirsutinolide Inhibitor / Unkown
HY-N9867 Gnetifolin E Inhibitor / Unkown
HY-P10241 Ac-LEHD-CHO Inhibitor / Unkown
HY-P10350 PapRIV Agonist / Unkown
HY-P10354 SPA4 / Unkown
HY-P1832 PTD-p65-P1 Peptide / Unkown
HY-P1847 IKKγ NBD Inhibitory Peptide / Unkown
HY-P2612 WP9QY Antagonist / Unkown
HY-P3149 LEESGGGLVQPGGSMK / Unkown
HY-P3149A LEESGGGLVQPGGSMK TFA / Unkown
HY-P3585 Epobis Inhibitor / Unkown
HY-P3722 Mca-PLAQAV-Dpa-RSSSR-NH2 / Unkown
HY-RS14784 TNF Human Pre-designed siRNA Set A / Unkown
HY-RS14785 Tnf Mouse Pre-designed siRNA Set A / Unkown
HY-RS14786 TNF Rat Pre-designed siRNA Set A / Unkown
HY-W010201R Citronellol (Standard) Activator / Unkown
HY-W014049 N'-Nitro-D-arginine Inhibitor / Unkown
HY-W104821 Rosolic acid Activator / Unkown
HY-108162 Ataquimast free base Inhibitor / Unkown
HY-110343 DBM 1285 dihydrochloride Inhibitor / Unkown
HY-156431 Anti-inflammatory agent 61 Inhibitor / Unkown
HY-157325 RIPK2-IN-5 Inhibitor / Unkown
HY-N1159 Teuclatriol Inhibitor / Unkown
HY-N11994 Aloeresin G Inhibitor / Unkown
HY-N12116 Maceneolignan A Inhibitor / Unkown
HY-N12840 Logmalicid B / Unkown
HY-N8015S1 Octanal-d2 Inhibitor / Unkown
HY-W015879S 2-Heptanol-d5 Inhibitor / Unkown
HY-W505984 TPNA10168 Activator / Unkown
HY-U00179 CDC801 Inhibitor 98.94% Unkown
Inhibitory Antibodies (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9908A Adalimumab (anti-TNF-α) Inhibitor 99.62% Unkown
HY-P990008 Atrosab 96.93% Unkown
HY-P99148 Anti-Mouse TNF alpha Antibody (TN3-19.12) Inhibitor ≥95.0% Unkown
HY-P99782 Opinercept Inhibitor / Unkown
HY-P99565 Tengonermin Inhibitor / Unkown
HY-P99692 Lenercept Inhibitor / Unkown
HY-P99753 Nerelimomab Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens TNF NCBI NCBI:7124
Canis familiaris TNF NCBI NCBI:403922
Macaca fascicularis TNF NCBI NCBI:102139631
Mus musculus TNF NCBI NCBI:21926
Susscrofa domestica TNF NCBI
Leporidae TNF NCBI
Macaca mulatta TNF NCBI NCBI:715467