IFI6 - interferon alpha inducible protein 6 Gene

Homo sapiens

Also known as 6-16; G1P3; FAM14C; IFI616; IFI-6-16

Gene ID: 2537 | Gene type: protein coding

About IFI6

Cytogenetic location: 1p35.3 Genomic coordinates (GRCh38): 1:27,666,064-27,672,192 (from NCBI)

This gene has 4 transcripts (splice variants), 89 orthologues and 3 paralogues. Broad expression in placenta (RPKM 111.6), salivary gland (RPKM 40.6) and 21 other tissues.

Summary

This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of Apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described. [provided by RefSeq, Jul 2008]

IFI6 Products(3)

mRNA	Protein	Name
NM_002038.4	NP_002029.3	interferon alpha-inducible protein 6 isoform a precursor
NM_022872.3	NP_075010.1	interferon alpha-inducible protein 6 isoform b precursor
NM_022873.3	NP_075011.1	interferon alpha-inducible protein 6 isoform c precursor

IFI6 Protein Structure

Ifi-6-16

0
100
130 a.a.

Protein Preferred Names

Protein Names

interferon alpha-inducible protein 6

interferon, alpha-inducible protein clone IFI-6-16

Related Diseases

Diseases

Alias

Dengue Virus

Dengue Virus, Susceptibility To	Dengue Fever, Protection Against
Dengue Fever