2. Gene
  3. Aldh3a1 - aldehyde dehydrogenase 3 family, member A1 Gene

Aldh3a1 - aldehyde dehydrogenase 3 family, member A1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as AHDC; Aldh; Ahd-c; Aldh3

Gene ID: 25375 | Gene type: protein coding

About Aldh3a1

Primary_assembly 10: 45,892,924-45,902,681 forward strand.mRatBN7.2:CM026983.1

This gene has 2 transcripts (splice variants), 370 orthologues, 20 paralogues and is associated with 5 phenotypes. Biased expression in Lung (RPKM 46.8), Heart (RPKM 25.7) and 4 other tissues.

Summary

Enables 3-chloroallyl aldehyde dehydrogenase activity. Involved in several processes, including response to cAMP; response to glucocorticoid; and response to hypoxia. Located in cytosol. Human ortholog(s) of this gene implicated in arteriosclerosis. Orthologous to human ALDH3A1 (aldehyde dehydrogenase 3 family member A1). [provided by Alliance of Genome Resources, Apr 2022]

Aldh3a1 Products(1)

mRNA Protein Name
NM_031972.2 NP_114178.1 aldehyde dehydrogenase, dimeric NADP-preferring

Aldh3a1 Protein Structure

ALDH_F3AB

ALDH_F3AB: cd07132 (4 - 446)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 453 a.a.
Protein Preferred Names Protein Names

aldehyde dehydrogenase, dimeric NADP-preferring

Aldehyde dehydrogenase (Ahd-c)

HTC-ALDH

aldehyde dehydrogenase 3A1

aldehyde dehydrogenase class 3

aldehyde dehydrogenase family 3 member A1

aldehyde dehydrogenase family 3 subfamily A1

tumor-associated aldehyde dehydrogenase tumor ALDH

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0364A Dyclonine hydrochloride Inhibitor 99.86% Unkown
Pre-clinical Phase
Bioactive Molecules (13)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-123962 G6PD activator AG1 Activator 98.38% Unkown
HY-W017186 ALDH1A3-IN-3 Inhibitor 99.12% Unkown
HY-146683 KS106 99.31% Unkown
HY-122577 EN40 Inhibitor 99.56% Unkown
HY-144670 ALDH3A1-IN-1 Inhibitor ≥95.0% Unkown
HY-144669 ALDH1A3-IN-2 Inhibitor 99.28% Unkown
HY-146682 KS100 99.61% Unkown
HY-144671 ALDH3A1-IN-2 Inhibitor / Unkown
HY-RS00571 ALDH3A1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00572 Aldh3a1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00573 Aldh3a1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00575 ALDH3B1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-125085 ALDH3A1-IN-3 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aldh3a1 NCBI NCBI:218