2. Gene
  3. BCL6B - BCL6B transcription repressor Gene

BCL6B - BCL6B transcription repressor Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as BAZF; ZNF62; ZBTB28

Gene ID: 255877 | Gene type: protein coding

About BCL6B

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,023,050-7,029,644 (from NCBI)

This gene has 6 transcripts (splice variants), 176 orthologues and 28 paralogues. Broad expression in fat (RPKM 17.2), lung (RPKM 14.1) and 22 other tissues.

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in several processes, including regulation of gene expression; regulation of inflammatory response; and type 2 immune response. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

BCL6B Products(1)

mRNA Protein Name
NM_181844.4 NP_862827.2 B-cell CLL/lymphoma 6 member B protein

BCL6B Protein Structure

BTB

BTB: BTB/POZ domain (28 - 134)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (342 - 366)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (370 - 394)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (398 - 423)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (427 - 450)

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  • 479 a.a.
Protein Preferred Names Protein Names

B-cell CLL/lymphoma 6 member B protein

B cell CLL/lymphoma 6B

Related Diseases

Diseases Alias
Lymphoma

Lymphoid Cancer

Lymphomas

Lymphoid Cancers

Lymphoid Neoplasm

Lymphoma Nos

Nhl - [Non-Hodgkin Lymphoma]

Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, Nos

Non-Hodgkin Malignant Lymphoma Nos
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01439 BCL6B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus BCL6B MGD MGI:1278332
Bos taurus BCL6B VGNC VGNC:57982
Rattus norvegicus BCL6B RGD RGD:1563179
Macaca mulatta BCL6B VGNC VGNC:70037
Canis familiaris BCL6B VGNC VGNC:58662