INTS7 - integrator complex subunit 7 Gene

Homo sapiens

Also known as INT7; C1orf73

Gene ID: 25896 | Gene type: protein coding

About INTS7

Cytogenetic location: 1q32.3 Genomic coordinates (GRCh38): 1:211,940,403-212,035,557 (from NCBI)

This gene has 11 transcripts (splice variants) and 204 orthologues. Broad expression in testis (RPKM 9.9), lymph node (RPKM 3.5) and 24 other tissues.

Summary

This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

INTS7 Products(4)

mRNA	Protein	Name
NM_001199809.2	NP_001186738.1	integrator complex subunit 7 isoform 4
NM_001199811.2	NP_001186740.1	integrator complex subunit 7 isoform 2
NM_001199812.2	NP_001186741.1	integrator complex subunit 7 isoform 3
NM_015434.4	NP_056249.1	integrator complex subunit 7 isoform 1

Protein Preferred Names

Protein Names

integrator complex subunit 7

Related Diseases

Diseases

Alias

Gastric Cancer

Stomach Cancer	Gastric Carcinoma
Stomach Carcinoma	Gastric Cancer, Somatic
Gastric Neoplasm	Carcinoma Of Stomach
Stomach Neoplasms	Malignant Neoplasm Of Stomach
Gastric Cancer Risk After H. Pylori Infection	Cancer Of The Stomach
Adult Stomach Cancer	Adult Stomach Carcinoma
GASC	Gastric Cancer Intestinal
Gastric Cancers	Gastric Carcinomas
Cancer, Gastric	Stomach Neoplasm
Malignant Neoplasm Of Body Of Stomach	Malignant Tumor Of Lesser Curve Of Stomach
Gastrocarcinoma Of Unspecified Site	Leather Bottle Stomach
Carcinoma Of Fundus Of Stomach	Cancer Of Fundus Of Stomach
Primary Malignant Neoplasm Of Body Of Stomach	Cancer Of Body Of Stomach
Primary Malignant Neoplasm Of Pyloric Antrum	Pyloric Antrum Cancer
Malignant Tumour Of Stomach

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06857	INTS7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	INTS7	RGD	RGD:1308014
Felis catus	INTS7	VGNC	VGNC:62947
Macaca mulatta	INTS7	VGNC	VGNC:73644
Bos taurus	INTS7	VGNC	VGNC:30233
Canis familiaris	INTS7	VGNC	VGNC:42056
Mus musculus	INTS7	MGD	MGI:1924315

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