2. Gene
  3. TIPARP - TCDD inducible poly(ADP-ribose) polymerase Gene

TIPARP - TCDD inducible poly(ADP-ribose) polymerase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as PARP7; ARTD14; pART14

Gene ID: 25976 | Gene type: protein coding

About TIPARP

Cytogenetic location: 3q25.31 Genomic coordinates (GRCh38): 3:156,674,590-156,706,770 (from NCBI)

This gene has 7 transcripts (splice variants), 208 orthologues and 8 paralogues. Ubiquitous expression in adrenal (RPKM 28.8), esophagus (RPKM 23.5) and 24 other tissues.

Summary

This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

TIPARP Products(6)

mRNA Protein Name
NM_001184717.1 NP_001171646.1 protein mono-ADP-ribosyltransferase TIPARP
XM_047447935.1 XP_047303891.1 protein mono-ADP-ribosyltransferase TIPARP isoform X1
XM_047447936.1 XP_047303892.1 protein mono-ADP-ribosyltransferase TIPARP isoform X2
NM_001184718.2 NP_001171647.1 protein mono-ADP-ribosyltransferase TIPARP
NM_015508.5 NP_056323.2 protein mono-ADP-ribosyltransferase TIPARP
XM_047447937.1 XP_047303893.1 protein mono-ADP-ribosyltransferase TIPARP isoform X2

TIPARP Protein Structure

PARP

PARP: Poly(ADP-ribose) polymerase catalytic domain (466 - 649)

  • 0
  • 200
  • 400
  • 600
  • 657 a.a.
Protein Preferred Names Protein Names

protein mono-ADP-ribosyltransferase TIPARP

ADP-ribosyltransferase diphtheria toxin-like 14

poly [ADP-ribose] polymerase 7

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14546 TIPARP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS14547 Tiparp Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS14548 Tiparp Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TIPARP VGNC VGNC:53609
Mus musculus TIPARP MGD MGI:2159210
Macaca mulatta TIPARP VGNC VGNC:82714
Felis catus TIPARP VGNC VGNC:102854
Canis familiaris TIPARP VGNC VGNC:52906
Rattus norvegicus TIPARP RGD RGD:1306171